1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1431A
    Butylparaben sodium
    Inhibitor
    Butylparaben sodium strongly influences the later stages of the spermatogenesis in the testis through the deterioration of hormonal control and/or RNA and protein synthesis.
    Butylparaben sodium
  • HY-146446R
    PXYC1 (Standard)
    Inhibitor
    Maltopentaose (Standard) is the analytical standard of Maltopentaose. This product is intended for research and analytical applications. Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin.
    PXYC1 (Standard)
  • HY-128850S2
    N-Acetyl-D-mannosamine-13C-1
    N-Acetyl-D-mannosamine-13C-1 is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)
    N-Acetyl-D-mannosamine-<sup>13</sup>C-1
  • HY-B0306S
    Prothionamide-d5
    Inhibitor
    Prothionamide-d5 is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy.
    Prothionamide-d<sub>5</sub>
  • HY-N3789
    Dunnianol
    Inhibitor
    Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).
    Dunnianol
  • HY-B1190S1
    Cefadroxil-d4 trifluoroacetate
    Inhibitor
    Cefadroxil-d4 (trifluoroacetate) is deuterium labeled Cefadroxil.
    Cefadroxil-d<sub>4</sub> trifluoroacetate
  • HY-66011AS3
    Moxifloxacin-d3-1 hydrochloride
    Inhibitor
    Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    Moxifloxacin-d<sub>3</sub>-1 hydrochloride
  • HY-168258
    Antibiofilm agent-13
    Inhibitor
    Antibiofilm agent-13 (compound 14b) is a potent antibacterial agent that displays a broad-spectrum antimicrobial activity. Antibiofilm agent-13 could disintegrate the integrity of bacterial cell membranes by destroying transmembrane potential and enhancing membrane permeability, and causing the generation of intracellular ROS and the leakage of DNA and proteins, ultimately leading to bacterial death. Antibiofilm agent-13 inhibits both Gram-positive bacteria (MIC of 0.5-1 μg/mL) and Gram-negative bacteria (MIC of 1-32 μg/mL).
    Antibiofilm agent-13
  • HY-158380
    UH-NIP-16
    Inhibitor
    UH-NIP-16 exhibits antimicrobial activity against Mycobacterium tuberculosis, with MIC50 of 1.86 and 3.05 μM, for pathogenic mycobacterial strains H37Rv and CDC1551. UH-NIP-16 synergizes with Streptomycin (HY-B1906), Isoniazid (HY-B0329), Ethambutol (HY-B0535) and Bedaquiline (HY-14881), potentiates their anti-tuberculosis activities.
    UH-NIP-16
  • HY-180887
    A-692345
    Inhibitor
    A-692345 is a naphthyridone antibiotic. A-692345 exhibits antibacterial activity against S. aureus with a MIC of 8 µg/mL. A-692345 can be used for antimicrobial research.
    A-692345
  • HY-P1259
    PR-39
    Inhibitor
    PR-39, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 reversibly binds to the α7 subunit of the proteasome and blocks degradation of NF-κB inhibitor IκBα by the ubiquitin-proteasome pathway. PR-39 stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice.
    PR-39
  • HY-146650
    LpxC-IN-9
    Inhibitor
    LpxC-IN-9 (compound 19) is a potent LpxC inhibitor. LpxC-IN-9 has antibacterial and hypotensive effects. LpxC-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    LpxC-IN-9
  • HY-P3116
    Thiocoraline
    Inhibitor
    Thiocoraline is a depsipeptide that can be isolated by marine Micromonospora. Thiocoraline has antitumor activity with IC50s of 0.002, 0.002, 0.01 and 0.002 μg/mL in P388, A549, HT-29 and MEL-28 cells, respectively. Thiocoraline also a strong antimicrobial activity against Gram-positive microorganisms.
    Thiocoraline
  • HY-N20632
    Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside
    Inhibitor
    Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside is a sortase A inhibitor of Streptococcus mutans, with an IC50 value of 94.3 μM. Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside inhibits saliva-induced aggregation of Streptococcus mutans. Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside can be used in caries-related research.
    Maltol-3-O-(4'-O-p-coumaroyl-6'-O-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside
  • HY-146119
    Antitubercular agent-24
    Inhibitor
    Antitubercular agent-24 (Compound 1) is an anti-tubercular agent with an extracellular IC50 of 0.83 μM and an intracellular IC50 of 0.17 μM against M. tuberculosis H37Rv.
    Antitubercular agent-24
  • HY-P5630
    Aeschna defensin
    Inhibitor
    Aeschna defensing is an antimicrobial peptide derived from hemolymph of dragonfly aquatic larvae. Aeschna defensing has strong activity against gram-positive bacteria.
    Aeschna defensin
  • HY-N3274
    Methyl isocostate
    Methyl isocostate (compound 24)has antibacterial activity that can be isolated from Globba schomburgkii.
    Methyl isocostate
  • HY-P5697
    Tilapia piscidin 3
    Inhibitor
    Tilapia piscidin 3 is an antimicrobial peptide with antibacterial activity against gram-positive and -negative bacteria (MIC: 2.44, 2.44, 9.78, 19.55, 0.61 μg/mL for V. vulnificus 204, V. alginolyticus, S. agalactiae 819, E. faecalis BCRC 10066, S. agalactiae BCRC 10787). Tilapia piscidin 3 has hemolytic activity in fish red blood cells.
    Tilapia piscidin 3
  • HY-P5829A
    CRAMP (140-173) (mouse) TFA
    Inhibitor
    CRAMP (140-173) (mouse) TFA is a ortholog of human LL-37 antimicrobial peptide. CRAMP (140-173) (mouse) TFA inhibits LPS (HY-D1056)-induced responses, and can not colocalized with TLR3 in BEAS-2B cells.
    CRAMP (140-173) (mouse) TFA
  • HY-121548
    Drimentine A
    Inhibitor
    Drimentine A is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria.nlike Drimentine B and Drimentine C, Drimentine A does not have anticancer activity.
    Drimentine A
Cat. No. Product Name / Synonyms Application Reactivity