HBV
Hepatitis B virus
HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.
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HBV Related Products (383)
Related Products (383)
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Antibodies (2)
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HBV-IN-17
0 ImagesCat. No.: HY-144320CAS No.: 2270943-13-8HBV-IN-17 (compound 8) is a potent HBV capsid assembly modulator with an EC50 of 511 nM.
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HBV-IN-9
0 ImagesCat. No.: HY-145052CAS No.: 2170998-69-1
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Lamivudine-13C,d2
0 ImagesCat. No.: HY-W654247CAS No.: 2714473-70-6Lamivudine-13C,d2 is the deuterium labeled and 13C-labeled Lamivudine. Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS.
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BA38017
0 ImagesCat. No.: HY-145871CAS No.: 1333905-67-1
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HBV-IN-43
0 ImagesCat. No.: HY-163124CAS No.: 2305897-05-4HBV-IN-43 (compound 5832) is a potent inhibitor of HBV.
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Elebsiran
0 ImagesCat. No.: HY-147266ACAS No.: 2648009-64-5Synonyms: VIR-2218Elebsiran (VIR-2218) is a siRNA that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. Elebsiran leads to a significant decrease in HBV surface antigen (HBsAg) and a reduction in viral load. Elebsiran binds to the sialic acid-depleted glycoprotein receptor (ASGPR) on the surface of liver cells through the GalNAc ligand, achieving liver-targeted delivery and demonstrating improved liver safety. Elebsiran can be used for the study of chronic HBV/HDV infections.
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Daplusiran sodium scrambled negative control
0 ImagesCat. No.: HY-177625BDaplusiran sodium scrambled negative control is the sequence scrambled negative control of Daplusiran sodium.
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HBV Seq1 aa:63-71
0 ImagesCat. No.: HY-P4049CAS No.: 189323-64-6
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Ozisiran
0 ImagesCat. No.: HY-177654CAS No.: 3061406-96-7
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MK-1220
0 ImagesCat. No.: HY-14404CAS No.: 924270-31-5MK-1220 is a covalently reversible inhibitor of the hepatitis C virus (HCV) NS3/4A protease (NS3/4A protease) with a Ki of 0.02 nM. MK-1220 in cell models simulating viral replication exhibits EC50s of 4 (with 10% fetal bovine serum) and 11 nM (50% normal human serum). MK-1220 can be used for the study of chronic hepatitis C virus infection.
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Pseudolaric Acid B (Standard)
0 ImagesPseudolaric Acid B (Standard) is the analytical standard of Pseudolaric Acid B. This product is intended for research and analytical applications. Pseudolaric Acid B is an orally active diterpene acid. Pseudolaric Acid B has anti-fungal, anti-fertility, anti-angiogenesis and anticancer activity, and can induce tumor cell apoptosis and autophagy. In addition, Pseudolaric Acid B can inhibit the secretion of hepatitis B virus (HBV) and has immunosuppressive effect, selectively inhibiting the proliferation of T lymphocytes and the production of IL-2.
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4-Hydroxyacetophenone (Standard)
0 Images4-Hydroxyacetophenone (Standard) is the analytical standard of 4-Hydroxyacetophenone. This product is intended for research and analytical applications. 4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer.
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HBV-IN-41
0 ImagesCat. No.: HY-156272CAS No.: 1967002-25-0HBV-IN-41 (compound 45) is a potent and orally active Hepatitis B Virus (HBV) inhibitor, with an EC50 of 0.027μM.
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Z060228
0 ImagesCat. No.: HY-109969CAS No.: 1005459-82-4
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GalNAc unconjugated/naked Xalnesiran
0 ImagesCat. No.: HY-145638XSynonyms: GalNAc unconjugated/naked RO7445482GalNAc unconjugated/naked Xalnesiran is a non-GalNAc-conjugated Xalnesiran (HY-145638). Xalnesiran is siRNA for the study of chronic hepatitis B (HBV).
