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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Produits associés (3819):

Cat. No. Nom du produit Effet Pureté Chemical Structure
  • HY-123253
    cis-LY393053
    cis-LY393053 is an active compound.
    cis-LY393053
  • HY-137052
    Lycorine methiodide
    Lycorine methiodide (N-Methyllycorine iodide) is a derivative of Lycorine (HY-N0288). Lycorine methiodide exhibits no significant in vitro antitumor activity against A549, OE21, Hs683, U373, SKMEL, and B16F10 cell lines, with all IC50 values greater than 10 μM.
    Lycorine methiodide
  • HY-N19872
    Mukurozioside IIb
    Mukurozioside IIb is a sesquiterpene glycoside found in S. mukorossi and Sapindus rarak. Mukurozioside IIb can be used for the research of breast cancer.
    Mukurozioside IIb
  • HY-W780717
    Ceftizoxime alapivoxil
    Ceftizoxime alapivoxil AS-924 (free base) is an orally active prodrug of Ceftizoxime (HY-B1596). Ceftizoxime alapivoxil exhibits potent inhibitory effect against gram-positive and gram-negative bacteria. Ceftizoxime alapivoxil can be used for the research of bacterial infection.
    Ceftizoxime alapivoxil
  • HY-106412A
    Stacofylline hydrochloride
    Stacofylline hydrochloride (S 9977), a Xanthine (HY-W017389) derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities.
    Stacofylline hydrochloride
  • HY-133627
    1,3-Dibromo-1,3-dichloroacetone
    1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant.
    1,3-Dibromo-1,3-dichloroacetone
  • HY-N18374
    Quercetin-3-O-[α-L-rhamnose-(1→2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside
    Quercetin-3-O--5-O-β-D-glucopyranoside is a flavone glycoside found in the seeds of Impatiens balsamina L.
    Quercetin-3-O-[α-L-rhamnose-(1→2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside
  • HY-N15543
    Thaigranatumin K
    Thaigranatumin K is a protolimonoid compound found in the seeds of the Thai mangrove (Xylocarpus granatum). Thaigranatumin K is promising for research of neurodegenerative diseases such as Parkinson's diseases.
    Thaigranatumin K
  • HY-139248
    Paclitaxel octadecanedioate
    Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively).
    Paclitaxel octadecanedioate
  • HY-N7685
    Podophyllol
    Podophyllol, a derivative of podophyllotoxin esters, has antitumor activity.
    Podophyllol
  • HY-N17420
    N-Fornzyl-annonain
    N-Formzyl-annonain is an N-acylaporphine alkaloid that occurs in the stems of Tinospora crispa (Menispermaceae).
    N-Fornzyl-annonain
  • HY-N2869
    Angeflorin
    Angeflorin is a natural flavonoid.
    Angeflorin
  • HY-N17096
    Lup-20(29)-ene-2α,3α-diol
    Lup-20(29)-ene-2α,3α-diol is a natural triterpene.
    Lup-20(29)-ene-2α,3α-diol
  • HY-W035404
    1-(1,3-Diphenylpropan-2-yl)pyrrolidine hydrochloride
    1-(1,3-Diphenylpropan-2-yl)pyrrolidine hydrochloride is structurally similar to known dissociative anesthetics.
    1-(1,3-Diphenylpropan-2-yl)pyrrolidine hydrochloride
  • HY-101680
    Zolasartan
    Zolasartan is an active compound.
    Zolasartan
  • HY-113704
    BKM1740
    BKM1740 is an active compound.
    BKM1740
  • HY-W004288R
    Methyl myristate (Standard)
    Methyl myristate (Standard) is the analytical standard of Methyl myristate. This product is intended for research and analytical applications. Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma.
    Methyl myristate (Standard)
  • HY-W142039
    Z-Nle-OH
    Z-Nle-OH is a leucine derivative.
    Z-Nle-OH
  • HY-139797
    SCH 47896
    SCH 47896 is a phenolic derivative of SCH39370 (HY-139803), a potent specific inhibitor of metalloendopeptidase (NEP). SCH 47896 can be used for the research of cardiovascular disease, such as hypertension.
    SCH 47896
  • HY-N16812
    Mulberrofuran V
    Mulberrofuran V is a natural phenolic compound.
    Mulberrofuran V