2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3819):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-177955
    α-Obscurine derivative-1
    α-Obscurine derivative-1 (Compound 7) is a α-Obscurine (HY-134036) derivative. α-Obscurine derivative-1 inhibits CaV3.1 ion channel current with an IC50 of 0.19 μM. α-Obscurine derivative-1 can be used in the research of neurological disorders.
    α-Obscurine derivative-1
  • HY-160800
    Bilirubin ditaurine
    Bilirubin ditaurine (BR-DT) is a mimetic compound of conjugated bilirubin. Bilirubin ditaurine can completely prevent the oxidation of phosphatidylcholine induced by reactive oxygen species in multilayer liposomes or micelles. Bilirubin ditaurine does not significantly decompose 18:2-OOH on its own, but it can greatly accelerate the decomposition of 18:2-OOH catalyzed by copper ions. Bilirubin ditaurine can be used to study the detoxification effect of conjugated bilirubin.
    Bilirubin ditaurine
  • HY-N1761
    16-Oxodiepiserratenediol
    16-Oxodiepiserratenediol (3alpha,21beta-Dihydroxyserrat-14-en-16-one) is a natural triterpene.
    16-Oxodiepiserratenediol
  • HY-N16809
    Zataroside B
    Zataroside B is a natural terpenoid.
    Zataroside B
  • HY-N18281
    Hazelnutin F
    Hazelnutin F is an indoleacetic acid glycoside found in the kernels of Corylus avellana L.. Hazelnutin F lacks significant antioxidant activity against ABTS and DPPH radicals.
    Hazelnutin F
  • HY-N17130
    8-Methyldisporopsin 4'-methyl ether
    8-Methyldisporopsin 4'-methyl ether is a natural flavonoid.
    8-Methyldisporopsin 4'-methyl ether
  • HY-N12122A
    (2E,4Z,8E)-Dehydropipernonaline
    (2E,4Z,8E)-Dehydropipernonaline is a natural product that can be found in Biba.
    (2E,4Z,8E)-Dehydropipernonaline
  • HY-118708
    WEB2347
    WEB2347 is an active compound.
    WEB2347
  • HY-138079
    2′,3′-cGMP triethylamine
    2′,3′-cGMP triethylamine (Guanosine 2',3'-cyclic phosphate triethylamine) is an active compound. 2′,3′-cGMP triethylamine can be used for various studies.
    2′,3′-cGMP triethylamine
  • HY-W717425
    SC-60
    SC-60 is a derivative of Sorafenib (HY-10201). SC-60 exerts its anti-tumor effect by activating the phosphatase activity of SHP-1, thereby inhibiting the STAT3 signaling pathway. SC-60 exhibits strong proliferation inhibitory activity in various hepatocellular carcinoma (HCC) cell lines. SC-60 downregulates the expression of downstream anti-apoptotic proteins (such as Bcl-2, Cyclin D1, Survivin), ultimately inducing caspase-dependent apoptosis. SC-60 significantly inhibits tumor growth in xenograft tumor models. SC-60 can be used for the study of HCC.
    SC-60
  • HY-N18287
    Tenuifoliose Q
    Tenuifoliose Q is an oligosaccharide ester esterified with acetic acid, benzoic acid and p-hydroxycinnamic acid, which can be isolated from the root bark of Polygala tenuifolia Willd.
    Tenuifoliose Q
  • HY-N7936
    Ophiopogonanone H
    Ophiopogonanone H is a natural product that can be found in Ophiopogon japonicus?(L. f.) Ker Gawl..
    Ophiopogonanone H
  • HY-N9054
    Ageratochromene dimer
    Ageratochromene dimer (Precocene II dimer) is a natural phenolic compound.
    Ageratochromene dimer
  • HY-106935A
    CGP 29030A
    CGP 29030A is an orally effective and specific analgesic agent. CGP 29030A inhibits nociceptive spinal cord neurons without affecting normal sensory functions. CGP 29030A also inhibits gamma motor neurons, which may be beneficial for studying pain disorders that occur concurrently due to increased motor activity (such as cramp, spasm).
    CGP 29030A
  • HY-137614
    Sp-GTPαS
    Sp-GTPαS is a phosphonothioate analog of GTP (HY-113225). Sp-GTPαS is more metabolically stable than GTP.
    Sp-GTPαS
  • HY-120077
    LY307452
    LY307452 is an active compound.
    LY307452
  • HY-N15790
    Deoxycholic acid disulfate sodium
    Deoxycholic acid disulfate sodium is a bile acid (BA).
    Deoxycholic acid disulfate sodium
  • HY-P11663
    Abantide
    Abantide is a cortistatin analogue with anti-inflammatory and immunomodulator effects.
    Abantide
  • HY-127043
    Pirbenicillin
    Pirbenicillin is an active compound.
    Pirbenicillin
  • HY-157065
    Flufenamate aluminum
    Flufenamate aluminum is an anti-inflammatory agent.
    Flufenamate aluminum