Bilirubin ditaurine
Bilirubin ditaurine (BR-DT) is a peroxyl radical scavenger and chain-breaking antioxidant that inhibits lipid peroxidation by undergoing addition reactions with pyrrole moieties and accelerates copper ion-catalyzed decomposition of lipid hydroperoxides. Bilirubin ditaurine is used in oxidative stress-related research.
For research use only. We do not sell to patients.
- CAS No.: 89771-93-7
- Formula: C37H46N6O10S2
- Molecular Weight:798.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Bilirubin ditaurine (BR-DT) (20 μM; 90 min) efficiently scavenges peroxyl radicals (n = 1.9) and completely prevents AAPH (HY-Y0525)-induced oxidation of phosphatidylcholine in multilamellar liposomes and micelles at concentrations as low as 20 μM[1].
Bilirubin ditaurine (250 μM; 30 min) greatly accelerates copper ion-catalyzed decomposition of linoleic acid hydroperoxide (20 μM), with only 1% of the hydroperoxide remaining after 10 min, but shows no such activity in the presence of iron ions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 89771-93-7
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Molecular Weight 798.93
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Formula C37H46N6O10S2
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SMILES
O=S(CCNC(CCC(C(C)=C(N1)/C=C2C(C=C)=C(C(N/2)=O)C)=C1CC3=C(C(C)=C(N3)/C=C4C(C)=C(C(N/4)=O)C=C)CCC(NCCS(=O)(O)=O)=O)=O)(O)=O
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Synonyms
BR-DT
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Stocker R, et al. Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile. Proceedings of the National Academy of Sciences of the United States of America. 1987 Nov;84(22):8130-4. [Content Brief]
[4]. Robinson SH, et al. Bilirubin excretion in rats with normal and impaired bilirubin conjugation: effect of phenobarbital. The Journal of clinical investigation. 1971 Dec;50(12):2606-13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bilirubin ditaurine Related Classifications
HY-160800 Related Classifications
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