Bilirubin Conjugate disodium
Based on 1 Customer Validation
Bilirubin Conjugate disodium is a peroxyl radical scavenger and chain-breaking antioxidant that inhibits lipid peroxidation by undergoing addition reactions with pyrrole moieties and accelerates copper ion-catalyzed decomposition of lipid hydroperoxides. Bilirubin Conjugate disodium is used in oxidative stress-related research.
For research use only. We do not sell to patients.
- Purity : 95.0%
- CAS No.: 68683-34-1
- Formula: C37H44N6Na2O10S2
- Molecular Weight:842.89
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Bilirubin Conjugate disodium (20 μM; 90 min) efficiently scavenges peroxyl radicals (n = 1.9) and completely prevents AAPH (HY-Y0525)-induced oxidation of phosphatidylcholine in multilamellar liposomes and micelles at concentrations as low as 20 μM[1].
Bilirubin Conjugate disodium (250 μM; 30 min) greatly accelerates copper ion-catalyzed decomposition of linoleic acid hydroperoxide (20 μM), with only 1% of the hydroperoxide remaining after 10 min, but shows no such activity in the presence of iron ions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 68683-34-1
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Appearance Solid
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Molecular Weight 842.89
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Formula C37H44N6Na2O10S2
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Color Orange to red
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SMILES
O=C1N=C(C(C=C)=C1C)/C=C2NC(CC3=C(CCC(NCCS(=O)(O[Na])=O)=O)C(C)=C(/C=C4NC(C(C=C)=C\4C)=O)N3)C(CCC(NCCS(=O)(O[Na])=O)=O)=C/2C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (118.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Stocker R, et al. Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile. Proceedings of the National Academy of Sciences of the United States of America. 1987 Nov;84(22):8130-4. [Content Brief]
[4]. Robinson SH, et al. Bilirubin excretion in rats with normal and impaired bilirubin conjugation: effect of phenobarbital. The Journal of clinical investigation. 1971 Dec;50(12):2606-13. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1864 mL | 5.9320 mL | 11.8639 mL | 29.6599 mL |
| 5 mM | 0.2373 mL | 1.1864 mL | 2.3728 mL | 5.9320 mL | |
| 10 mM | 0.1186 mL | 0.5932 mL | 1.1864 mL | 2.9660 mL | |
| 15 mM | 0.0791 mL | 0.3955 mL | 0.7909 mL | 1.9773 mL | |
| 20 mM | 0.0593 mL | 0.2966 mL | 0.5932 mL | 1.4830 mL | |
| 25 mM | 0.0475 mL | 0.2373 mL | 0.4746 mL | 1.1864 mL | |
| 30 mM | 0.0395 mL | 0.1977 mL | 0.3955 mL | 0.9887 mL | |
| 40 mM | 0.0297 mL | 0.1483 mL | 0.2966 mL | 0.7415 mL | |
| 50 mM | 0.0237 mL | 0.1186 mL | 0.2373 mL | 0.5932 mL | |
| 60 mM | 0.0198 mL | 0.0989 mL | 0.1977 mL | 0.4943 mL | |
| 80 mM | 0.0148 mL | 0.0741 mL | 0.1483 mL | 0.3707 mL | |
| 100 mM | 0.0119 mL | 0.0593 mL | 0.1186 mL | 0.2966 mL |
Bilirubin Conjugate disodium Related Classifications
HY-129834 Related Classifications
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