2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative 관련 제품 (3819):

Cat. No. 상품명 효과 Purity Chemical Structure
  • HY-N13748
    Simulanol
    Simulanol is a natural lignan.
    Simulanol
  • HY-178921
    HJ-4
    		98.02%
    HJ-4 is a Piperine (HY-N0144) derivative. HJ-4 potently inhibits the proliferation of CRC cells by dose-dependently reducing colony formation and DNA synthesis. HJ-4 markedly suppresses the adhesion, migration, invasion and induces apoptosis of CRC cells. HJ-4 demonstrates anti-tumor efficacy in chicken embryo chorioallantoic membrane (CAM) model implanted with HCT116/SW480 tumor spheroids. HJ-4 can be used for the study of colorectal cancer (CRC).
    HJ-4
  • HY-N16466
    Valerenal
    Valerenal (Nardal) is a sesquiterpene found in Valeriana officinalis root oil. Valerian root can be used as an herbal sedative which is helpful in the treatment of insomnia.
    Valerenal
  • HY-N17015
    1,3,5,7-Tetrahydroxy-8-isoprenylxanthone
    1,3,5,7-Tetrahydroxy-8-isoprenylxanthone is a natural xanthone.
    1,3,5,7-Tetrahydroxy-8-isoprenylxanthone
  • HY-106412
    Stacofylline
    Stacofylline (S 9977 free base; S 9977-2 free base), a Xanthine (HY-W017389) derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities.
    Stacofylline
  • HY-N15557
    Thaigranatumin D
    Thaigranatumin D is a protolimonoid compound found in the seeds of the Thai mangrove (Xylocarpus granatum). Thaigranatumin D is promising for research of neurodegenerative diseases such as Parkinson's diseases.
    Thaigranatumin D
  • HY-N17415
    Lyciumin C
    Lyciumin C is a monocyclic octapeptide containing a novel C-N linkage between tryptophan N1 and glycine Cα, and can be found in the root bark of Lycium chinense MILL.
    Lyciumin C
  • HY-171443
    Lyso-Monosialoganglioside GM3
    Lyso-Monosialoganglioside GM3 (Lyso-GM3) is an analogue of Ganglioside GM3 (HY-114456) with antitumor activities. Lyso-Monosialoganglioside inhibits EGF-induced increases in EGFR kinase activity in A431 epithelial cancer cells.
    Lyso-Monosialoganglioside GM3
  • HY-148157
    Amylocaine
    		98.26%
    Amylocaine is a local agent that can suppress or relieve pain of the ester type. Amylocaine can cause reversible insensitization near the area where it is administered. Amylocaine is used mostly in spinal anesthesia.
    Amylocaine
  • HY-177208
    BW-AQ-113
    BW-AQ-113 is an Anthraquinone (HY-N0354) derivative. BW-AQ-113 can specifically degrade MDM2 and activate the p53 pathway. BW-AQ-113 can induce apoptosis by downregulating anti-apoptotic gene Bcl-2 and regulating pro-apoptotic gene Bax and CASP3. BW-AQ-113 can be used for research of p53 wild-type hematological malignancies.
    BW-AQ-113
  • HY-W782495
    Cucurbitaxanthin A
    Cucurbitaxanthin A (Capsolutein) is a peculiar carotenoid containing an 3,6-oxabicycloheptane end group. Cucurbitaxanthin A is a carotenoid pigment.
    Cucurbitaxanthin A
  • HY-135326R
    4-Propionamidophenol (Standard)
    4-Propionamidophenol (Standard) is the analytical standard of 4-Propionamidophenol. This product is intended for research and analytical applications. 4-Propionamidophenol is an important intermediate of alkanolamine derivatives with β-adrenergic blocking activity. 4-Propionamidophenol can be used in the study of diseases such as heart disease and hypertension.
    4-Propionamidophenol (Standard)
  • HY-N7908
    1-Hydroxy-3,4,5-trimethoxyxanthone
    1-Hydroxy-3,4,5-trimethoxyxanthone is a natural product that can be found in Rubia cordifolia?L..
    1-Hydroxy-3,4,5-trimethoxyxanthone
  • HY-N15577
    Antiproliferative agent-69
    Antiproliferative agent-69 (Compound 1) is a prenylated kaempferol derivative found in the fresh bud’s fur of Platanus acerifolia. Antiproliferative agent-69 shows significant antiproliferative effects against human breast cancer cells (MCF-7) and human hepatocellular carcinoma cells (Hep-G2) with IC50 values of 38.2 μM and 39.5 μM, respectively. Antiproliferative agent-69 is promising for research of breast cancer and liver cancer.
    Antiproliferative agent-69
  • HY-123180
    Ro 31-2201
    Ro 31-2201 is an active compound.
    Ro 31-2201
  • HY-N13762
    Minisecolide D
    Minisecolide D is a natural steroid.
    Minisecolide D
  • HY-N16678A
    7-epi-Teucrenone
    7-epi-Teucrenone is a natural sesquiterpene.
    7-epi-Teucrenone
  • HY-121274
    Dicyclonon
    Dicyclonon is an active compound.
    Dicyclonon
  • HY-N16920
    Baccatin X
    Baccatin X is a natural diterpene.
    Baccatin X
  • HY-N9700
    (+)-Fargesin
    (+)-Fargesin is a natural lignan.
    (+)-Fargesin