2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-171478
    SQ 11,447
    SQ 11,447 is a methylurea analogue that demonstrates remarkable resistance to hydrolysis in both in vitro (rat, dog, and human liver homogenates) and in vivo (rat) experimental models.
    SQ 11,447
  • HY-183197
    SR 13915
    SR 13915 is a structural analog of EGCG (HY-13653), a green tea polyphenol, and exhibits an IC50 greater than 100 μM against both MCF‑7 and MDA‑MB‑231 cell lines.
    SR 13915
  • HY-172844
    3-Ethoxy-4-methoxy N,N-diethylpentedrone hydrochloride
    3-Ethoxy-4-methoxy N,N-diethylpentedrone hydrochloride is a drug analogue that can be used in the research of mental disorders.
    3-Ethoxy-4-methoxy N,N-diethylpentedrone hydrochloride
  • HY-114746
    25H-NBOMe imine analog
    25H-NBOMe imine analog is a biomolecule.
    25H-NBOMe imine analog
  • HY-N7352
    Stachartin E
    Stachartin E is a natural sesquiterpene.
    Stachartin E
  • HY-W728151
    3-O-Caffeoylshikimic acid
    3-O-Caffeoylshikimic acid is a caffeoylshikimic acid substance and phenolic acid that widely exists in the aerial parts of Equisetum arvense L. and Smilax glabra. During sulfur fumigation processing, 3-O-Caffeoylshikimic acid undergoes chemical transformation to produce 3-O-caffeoylshikimic acid sulfate and 3-O-caffeoylshikimic acid sulfite. At a high concentration (40 μM), 3-O-Caffeoylshikimic acid exhibits cytotoxic activity against human keratinocytes.
    3-O-Caffeoylshikimic acid
  • HY-168407
    7-Methoxy DiPT hydrochloride
    7-Methoxy DiPT hydrochloride is structurally categorized as a Tryptamine (HY-B2132).
    7-Methoxy DiPT hydrochloride
  • HY-B1061R
    Nicotinic acid N-oxide (Standard)
    Nicotinic acid N-oxide (Standard) is the analytical standard of Nicotinic acid N-oxide. This product is intended for research and analytical applications. Nicotinic acid N-oxide can be used for research on hyperlipidemia.
    Nicotinic acid N-oxide (Standard)
  • HY-W011334
    Methyl 12-oxooctadecanoate
    		98.0%
    Methyl 12-oxooctadecanoate is a fatty acid that can be isolated from the pulp of Livistona decipiens (Palmae), which has anti-hyperlipidemic and anti-ulcer activities.
    Methyl 12-oxooctadecanoate
  • HY-N15566
    Theleganbanin D
    Theleganbanin D is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin D inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin D is promising for research of neurodegenerative diseases .
    Theleganbanin D
  • HY-176017
    2,3-Dinor fluprostenol
    2,3-Dinor fluprostenol is a derivative of the FP receptor agonist and prostaglandin F2α (PGF2α) analog fluprostenol (HY-136494) .
    2,3-Dinor fluprostenol
  • HY-W178699
    (±)-Neoisomenthol
    (±)-Neoisomenthol is a monoterpene. (±)-Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. (±)-Neoisomenthol is a chiral compound, existing as a racemic mixture of two enantiomers, (+)-Neoisomenthol and (-)-Neoisomenthol.
    (±)-Neoisomenthol
  • HY-129860
    N-Chloroacetyl-L-tryptophan
    N-Chloroacetyl-L-tryptophan (Chloroacetyltryptophan) is a hydrolyzable tryptophan derivative. N-Chloroacetyl-L-tryptophan rapidly hydrolyzes to tryptophan in Pseudomonas aurantiaca cultures. N-Chloroacetyl-L-tryptophan increases the level of the antibiotic Pyrrolnitrin (HY-133704) in Pseudomonas aurantiaca fermentation cultures.
    N-Chloroacetyl-L-tryptophan
  • HY-157901
    2,3-Dihydroxybutanoic acid
    2,3-Dihydroxybutanoic acid is an anticancer agent that can be extracted from the leaves of Corydalis. 2,3-Dihydroxybutanoic acid has anticancer activity both in vitro and in vivo and is lethal to Ehrlich ascites tumor cells.
    2,3-Dihydroxybutanoic acid
  • HY-W1141596
    N-Acetylgalactosamine trimer
    N-Acetylgalactosamine trimer (the second structure in example 59) is a trimer of N-Acetylgalactosamine. N-Acetylgalactosamine trimer can be used for liver-targeted delivery of oligonucleotides.
    N-Acetylgalactosamine trimer
  • HY-N15730
    3-Hydroxymycophenolic acid
    3-Hydroxymycophenolic acid (Compound 5) is a microbial transformation product of Mycophenolic acid (HY-B0421) by Cunninghamella echinulata. 3-Hydroxymycophenolic acid has low cytotoxicity against AGS cells and fibroblasts. 3-Hydroxymycophenolic acid can be used for immune-mediated renal diseases research.
    3-Hydroxymycophenolic acid
  • HY-150343
    (±)-3-Methyl nimetazepam
    (±)-3-Methyl nimetazepam is a benzodiazepine.
    (±)-3-Methyl nimetazepam
  • HY-131368A
    α,α-Trehalose 6-phosphate
    α,α-Trehalose 6-phosphate (Tre6P) is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP).
    α,α-Trehalose 6-phosphate
  • HY-168385
    1,3-Dimyristoyl-2-oleoylglycerol
    1,3-Dimyristoyl-2-oleoylglycerol is a crystal structure of the beta1 polymorphs of mono-unsaturated triacylglycerols.
    1,3-Dimyristoyl-2-oleoylglycerol
  • HY-109088
    Enexasogaol
    Enexasogaol (trans-6-Shogaol; (E)-[6]-Shogaol) is the derivative of Shogaol (HY-14616) found in Ginger (Zingiber officinale Rosc). Enexasogaol can be used for the research of cancer .
    Enexasogaol