2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3817):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-176014
    17-Phenyl trinor prostaglandin F2α glycinamide
    17-phenyl trinor PGF2α glycinamide (17-Phenyl trinor PGF2α glycinamide) is a derivative of 17-phenyl trinor prostaglandin F2α ethyl amide.
    17-Phenyl trinor prostaglandin F2α glycinamide
  • HY-119853
    Bayer A 139
    Bayer A 139 is an ethylene-menaquinone that inactivates fowl plaque virus activity. Bayer A 139 can react with nucleic acids at pH ≦ 7.
    Bayer A 139
  • HY-B1149AR
    Bacampicillin (hydrochloride) (Standard)
    Bacampicillin (hydrochloride) (Standard) is the analytical standard of Bacampicillin hydrochloride (HY-B1149A). This product is intended for research and analytical applications. Bacampicillin hydrochloride is an orally active semi-synthetic aminopenicillin derivative, prodrug and bactericide that is readily inactivated by β-lactamases. Bacampicillin hydrochloride is hydrolyzed by carboxylester hydrolases and non-specific esterases in the gastrointestinal wall and plasma to form Ampicillin (HY-B0522), and produces higher levels of Ampicillin in rodents in vivo. Bacampicillin hydrochloride exhibits bactericidal activity against Gram-positive and Gram-negative bacteria. Bacampicillin hydrochloride can be used in studies related to bacterial infections.
    Bacampicillin (hydrochloride) (Standard)
  • HY-120858
    25T4-NBOMe hydrochloride
    		99.24%
    25T4-NBOMe hydrochloride is a derivative of 2C-T-4, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine.
    25T4-NBOMe hydrochloride
  • HY-150349
    (±)-3-Methyl nitrazepam
    (±)-3-Methyl nitrazepam is a benzodiazepine.
    (±)-3-Methyl nitrazepam
  • HY-172032
    4'-Fluoro-α-pyrrolidinopropiophenone hydrochloride
    4'-Fluoro-α-pyrrolidinopropiophenone hydrochloride is a derivative of α-Pyrrolidinopropiophenone.
    4'-Fluoro-α-pyrrolidinopropiophenone hydrochloride
  • HY-13325
    Aβ aggregation modulator-1
    Aβ aggregation modulator-1 is a stimulator of amyloid-β (Aβ) fibrillogenesis. Aβ aggregation modulator-1 binds hydrophobic residues in Aβ peptides and stabilizes β-sheet-rich protofibrils and fibrils. Aβ aggregation modulator-1 accelerates Aβ polymerization and reduces concentrations of small, toxic Aβ oligomers in heterogeneous aggregation reactions. Aβ aggregation modulator-1 suppresses long-term potentiation (LTP) inhibition by Aβ oligomers in hippocampal brain slices. Aβ aggregation modulator-1 can be used for the study of Alzheimer's disease (AD).
    Aβ aggregation modulator-1
  • HY-W738288
    Rifamdin
    Rifamdin is a derivative of Rifampicin (HY-B0272). Rifamdin is an anti-tuberculosis agent. Rifamdin exerts its antibacterial effect by inhibiting the synthesis of bacterial RNA.
    Rifamdin
  • HY-128413
    1-Iodoadamantane
    1-Iodoadamantane is a 1-substituted adamantane derivative. On a silver electrode in aprotic solvents, 1-Iodoadamantane can be reduced to form a mixture of adamantane and 1,1'-biadamantane without insonation, while only adamantane is formed under the action of 10 kHz insonation.
    1-Iodoadamantane
  • HY-W708286
    α-Pyrrolidinobutiothiophenone hydrochloride
    α-Pyrrolidinobutiothiophenone hydrochloride is a synthetic drug derivative.
    α-Pyrrolidinobutiothiophenone hydrochloride
  • HY-182341
    APD-209
    APD-209 is a sialic acid conjugate with a PEG4 polar linker and a PDA non-polar tail. APD-209 aggregates adenovirus type 37 particles, blocks the binding of viral particles to human corneal epithelial cells, and inhibits cellular entry of adenovirus type 37. APD-209 can be used for the research of epidemic keratoconjunctivitis.
    APD-209
  • HY-171004
    KRN7000 analog 8
    KRN7000 analog 8 (compound 8), KRN7000 (HY-102022) analogue, shows a good stimulatory effect on IL-2 production, induced less IFN-γ but more IL-4 production compared with KRN7000.
    KRN7000 analog 8
  • HY-W142701
    Succinamide
    		≥98.0%
    Succinamide is an amide derivative of succinic acid. Succinamide is the parent compound of some anticonvulsant drugs, proteins, plastic adhesives. Succinamide can be used in biochemical experiments and in the synthesis of other compounds.
    Succinamide
  • HY-Y1668
    Trimethylacetaldehyde
    Trimethylacetaldehyde (Pivalic aldehyde) is an analog of Betaine aldehyde. Trimethylacetaldehyde has a significant enzyme inhibitory activity towards betaine aldehyde dehydrogenase. Trimethylacetaldehyde can be used for osmoprotectants of E.coli research.
    Trimethylacetaldehyde
  • HY-168832
    N-Benzyl-3,4-DMA hydrochloride
    N-Benzyl-3,4-DMA hydrochloride is an amphetamine.
    N-Benzyl-3,4-DMA hydrochloride
  • HY-Y0123R
    DL-Tyrosine (Standard)
    DL-Tyrosine (Standard) is the analytical standard of DL-Tyrosine (HY-Y0123). This product is intended for research and analytical applications. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine).
    DL-Tyrosine (Standard)
  • HY-123043A
    Afeletecan hydrochloride
    Afeletecan hydrochloride is an ester prodrug.
    Afeletecan hydrochloride
  • HY-168408
    5-AEDB hydrochloride
    5-AEDB hydrochloride is a benzofuran.
    5-AEDB hydrochloride
  • HY-W015131
    3-(4-(Dimethylamino)phenyl)acrylic acid
    3-(4-(Dimethylamino)phenyl)acrylic acid is a Alkaloids product that can be isolated from the barks of Cinnamomum cassia Presl.
    3-(4-(Dimethylamino)phenyl)acrylic acid
  • HY-163060
    Metronidazole phosphate disodium
    Metronidazole phosphate disodium is a water-soluble prodrug for parenteral solutions of Metronidazole (HY-B0318). Metronidazole phosphate disodium is an antibiotic and can be used for the research of anaerobic infections.
    Metronidazole phosphate disodium