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  3. Drug Derivative
  4. APD-209

APD-209 is a sialic acid conjugate with a PEG4 polar linker and a PDA non-polar tail. APD-209 aggregates adenovirus type 37 particles, blocks the binding of viral particles to human corneal epithelial cells, and inhibits cellular entry of adenovirus type 37. APD-209 can be used for the research of epidemic keratoconjunctivitis.

For research use only. We do not sell to patients.

APD-209

APD-209 Chemical Structure

CAS No. : 1261156-82-4

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APD-209 Related Antibodies

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Description

APD-209 is a sialic acid conjugate with a PEG4 polar linker and a PDA non-polar tail. APD-209 aggregates adenovirus type 37 particles, blocks the binding of viral particles to human corneal epithelial cells, and inhibits cellular entry of adenovirus type 37. APD-209 can be used for the research of epidemic keratoconjunctivitis[1].

In Vitro

APD-209 (Compound 8b) exerts the strongest inhibitory effect on the binding of Ad37 to human corneal epithelial (HCE) cells, with an IC50 of 0.9 μM[1].
APD-209 inhibits Ad37 infection in human corneal epithelial (HCE) cells, with an IC50 of 0.7 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

APD-209 Related Antibodies
Molecular Weight

1042.34

Formula

C54H95N3O16
CAS No.
SMILES

O=C(NCCOCCOCCOCCOCCOCCC(NCCCCCO[C@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O)=O)CCCCCCCCC#CC#CCCCCCCCCCCCC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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APD-209 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

APD-2091261156-82-4APD209APD 209Drug DerivativeDrug derivativenegative stain transmission electron microscopyHCE cellshuman corneal epithelial cellsAd37PDAepidemic keratoconjunctivitisadenovirus type 37virionsPEG4sialic acidInhibitorinhibitorinhibit

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