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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-106873A
    Nepinalone hydrochloride
    		99.59%
    Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity.
    Nepinalone hydrochloride
  • HY-115738
    2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose
    		99.60%
    2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose (Compound 13) is a 2-acetamido-2-deoxy-D-glucose analog. 2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose is applicable to research related to glycosaminoglycan biosynthesis.
    2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose
  • HY-185323
    Gem-C12
    		98.02%
    Gem-C12 is a prodrug of Gemcitabine (HY-17026). Gem-C12 terminates DNA chain elongation, inhibits nucleic acid synthesis and induces Apoptosis. Gem-C12 inhibits the proliferation of glioma cells. Gem-C12 and Honokiol (HY-N0003) exhibit synergistic anti-glioblastoma activity. Gem-C12 can be used in research related to glioblastoma multiforme.
    Gem-C12
  • HY-121870
    Dimethocaine
    		99.90%
    Dimethocaine (Larocaine) is a cocaine derivative and ester-type local anesthetic. Dimethocaine is metabolized by hP450 1A2, 2C19, 2D6, and 3A4 in vitro. Dimethocaine exhibits locomotor-promoting, reinforcing, and anxiogenic effects.
    Dimethocaine
  • HY-N3434
    Kaempferol 3,7,4'-trimethyl ether
    		99.97%
    Kaempferol 3,7,4'-trimethyl ether is an O-methylated kaempferol flavonol aglycone distributed in Siparuna gigantotepala, Aframomum arundinaceum and Siparuna guianensis. Kaempferol 3,7,4'-trimethyl ether exhibits antioxidant activity. Kaempferol 3,7,4'-trimethyl ether suppresses the proliferation of leukemia cells and exerts selective cytotoxicity against both drug‑sensitive and multi‑factorial drug‑resistant cancer cells. Kaempferol 3,7,4'-trimethyl ether can be applied in the research of multidrug‑resistant cancers.
    Kaempferol 3,7,4'-trimethyl ether
  • HY-124198
    2,1,3-Benzoselenadiazole
    		99.31%
    2,1,3-Benzoselenadiazole is an active compound.
    2,1,3-Benzoselenadiazole
  • HY-402939A
    N-sec-butyl Pentylone hydrochloride
    		99.0%
    N-sec-butyl Pentylone hydrochloride is a drug derivative.
    N-sec-butyl Pentylone hydrochloride
  • HY-179537
    CKBA
    CKBA, a derivative of AKBA (HY-N0892) is an inhibitor of acetyl-CoA carboxylase 1 (ACC1), with an IC50 of 5.02 μM. CKBA inhibits the differentiation of Th17 cells and has IC50 values of 3.28 μM for mouse cells and 3.61 μM for human cells. CKBA ointment significantly alleviates psoriasis-like inflammation in mice. CKBA can be used for the study of psoriasis.
    CKBA
  • HY-137961
    Cannabigerol monomethyl ether
    		98.04%
    Cannabigerol monomethyl ether is a monomethyl ether derivative of the canonical phytocannabinoids.
    Cannabigerol monomethyl ether
  • HY-148484
    Pomalidomide-5'-PEG5-C2-COOH
    		98.08%
    Pomalidomide-5'-PEG5-C2-COOH is an active compound. Pomalidomide-5'-PEG5-C2-COOH can be used for the research of various biochemical.
    Pomalidomide-5'-PEG5-C2-COOH
  • HY-W783283
    18:1 (8-cis) PC
    		≥99.0%
    18:1 (8-cis) PC is a phospholipid.
    18:1 (8-cis) PC
  • HY-B0910
    Pyrithioxin
    		99.93%
    Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis.
    Pyrithioxin
  • HY-156562
    5-PT
    5-PT (5-Propargyltryptamide) is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT can be used for the research of bronchopulmonary dysplasia.
    5-PT
  • HY-W016215
    5-Chloro-2-benzothiazolinone
    		99.0%
    5-Chloro-2-benzothiazolinone is an active compound. 5-Chloro-2-benzothiazolinone can be used for the research of various biochemical studies.
    5-Chloro-2-benzothiazolinone
  • HY-115378
    1-(3,5-Dimethylphenyl)piperazine
    		98.90%
    1-(3,5-Dimethylphenyl)piperazine is a piperidine compound.
    1-(3,5-Dimethylphenyl)piperazine
  • HY-B2191R
    Sodium gualenate (Standard)
    Sodium gualenate (Standard) is the analytical standard of Sodium gualenate. This product is intended for research and analytical applications. Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
    Sodium gualenate (Standard)
  • HY-158812
    Eicosapentaenoyl-L-carnitine chloride
    Eicosapentaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Eicosapentaenoic Acid (HY-B0660) and L-Carnitine (HY-B0399). The levels of Eicosapentaenoyl-L-carnitine chloride are increased in the eyes of mice fed a diet high in n-3/n-6 polyunsaturated fatty acids (PUFAs) in a mouse model of myopia induced by out-of-focus lenses.
    Eicosapentaenoyl-L-carnitine chloride
  • HY-166238
    rel-Linoleic acid-biotin
    rel-Linoleic acid-biotin is an ester product.
    rel-Linoleic acid-biotin
  • HY-W012816
    2-Methylresorcinol
    		98.99%
    2-Methylresorcinol is a tripyrrane analog. 2-Methylresorcinol is a cosmetic ingredient with endocrine activity. 2-Methylresorcinol combined with Butylhydroxyanisole (HY-B1066) and Avobenzone (HY-B0316) has anti-glucocorticoid-like activity. 2-Methylresorcinol combined with Avobenzone only has anti-androgen-like activity. 2-Methylresorcinol can be used as for cosmetic industry.
    2-Methylresorcinol
  • HY-W749980
    Coronaric acid
    		≥98.0%
    Coronaric acid (cis-9,10-Epoxy-cis-12-octadecenoic acid) is an ester product.
    Coronaric acid