2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-121317
    Leucinocaine
    Leucinocaine is an active compound.
    Leucinocaine
  • HY-W750723
    Rubixanthin
    Rubixanthin, a carotenoid, is mainly derived from the biosynthesis process of carotenoids in the Flavobacterium strain R-1519.
    Rubixanthin
  • HY-N16926
    Chingchengenamide A
    Chingchengenamide A is a natural alkaloid.
    Chingchengenamide A
  • HY-132822A
    Ivospemin hydrochloride
    Ivospemin (SBP-101) hydrochloride is an antineoplastic spermine analog. Ivospemin hydrochloride has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin hydrochloride shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin hydrochloride is promising for research of cancers.
    Ivospemin hydrochloride
  • HY-121352
    Kibdelone C
    		98.4%
    Kibdelone C is a hexacyclic tetrahydroxanthone natural product and anticancer agent with sub-nanomolar GI50 activity against human SR leukemia and SN12C renal carcinoma cell lines. Kibdelone C disrupts the actin cytoskeleton in human cancer cells, leading to cell contraction and actin stress fiber formation, without direct actin binding, actin polymerization effects, topoisomerase I/II inhibition, or DNA binding. Kibdelone C can be used for the research of leukemia, and renal cell carcinoma.
    Kibdelone C
  • HY-100167
    TAK-778
    		Inducer
    TAK-778 is a derivative of ipriflavone and has been shown to induce bone growth in in vitro and in vivo models.
    TAK-778
  • HY-176908
    SIOC-XJC-SF02
    SIOC-XJC-SF02 is a Fenofibrate (HY-17356) derivative. SIOC-XJC-SF02 induces Apoptosis. SIOC-XJC-SF02 exhibits significant anti-cancer activity against hepatocellular carcinoma.
    SIOC-XJC-SF02
  • HY-105166A
    S 16020-2
    S 16020-2 is a new Olivacine derivative. S 16020-2 shows antitumor activity S 16020-2 has anti-cancer activity against leukemia, sarcoma, lung cancer, non-small cell lung cancer, and breast cancer.
    S 16020-2
  • HY-W348226
    MMDPPA
    MMDPPA is an amphetamine and is a precursor in the synthesis of MDA.
    MMDPPA
  • HY-N19936
    Qinyangshengenin-3-O-β-D-digitoxopyranoside
    Qinyangshengenin-3-O-β-D-digitoxopyranoside is a C21 steroidal glycoside that can be found in the whole herb of Prunella vulgaris Linn. Qinyangshengenin-3-O-β-D-digitoxopyranoside can be used for research of leukemia and lung cancer.
    Qinyangshengenin-3-O-β-D-digitoxopyranoside
  • HY-177884
    Triptolide-6-β-D-glucose
    Triptolide-6-β-D-glucose (Compound 5) is a glucose-conjugated derivative of Triptolide (HY-32735). Triptolide-6-β-D-glucose has no effective anti-tumor activity and is mainly used for studying the structural-activity relationship (SAR) of derivatives.
    Triptolide-6-β-D-glucose
  • HY-164217
    β-D-Glucuronylmonomethylauristatin E
    β-D-Glucuronylmonomethylauristatin E is a derivative of MMAE (HY-15162). β-D-Glucuronylmonomethylauristatin E does not interact with pure phospholipid membranes, but can be effectively solubilized by micelles.
    β-D-Glucuronylmonomethylauristatin E
  • HY-139409B
    2-Deoxy-D-glucose 6-phosphate sodium
    2-Deoxy-D-glucose 6-phosphate sodium, a derivative of 2-Deoxy-D-glucose (HY-13966), is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
    2-Deoxy-D-glucose 6-phosphate sodium
  • HY-N13804
    2'-Hydroxyneophellamuretin
    2'-Hydroxyneophellamuretin is a natural flavonoid.
    2'-Hydroxyneophellamuretin
  • HY-N17291
    2,6,2',6'-Tetramethoxy-4,4'-bis(2,3-epoxy-1-hydroxypropyl)biphenyl
    2,6,2',6'-Tetramethoxy-4,4'-bis(2,3-epoxy-1-hydroxypropyl)biphenyl (compound 1) is a biphenylneolignan that can be found in the roots of Cynanchum atratum.
    2,6,2',6'-Tetramethoxy-4,4'-bis(2,3-epoxy-1-hydroxypropyl)biphenyl
  • HY-B0172AR
    Isoallolithocholic acid (Standard)
    Isoallolithocholic acid (Standard) is the analytical standard of Isoallolithocholic acid. This product is intended for research and analytical applications. Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation[1].
    Isoallolithocholic acid (Standard)
  • HY-49069
    Anti-osteoporosis agent-7
    		99.47%
    Anti-osteoporosis agent-7 (Compound 133) is a potential anti-osteoporosis agent showing high inhibition of osteoclast formation.
    Anti-osteoporosis agent-7
  • HY-N7876
    Ejaponine B
    Ejaponine B is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..
    Ejaponine B
  • HY-164681
    Sunepitron
    Sunepitron is an active compound.
    Sunepitron
  • HY-N9957
    Leontopodic acid A
    Leontopodic acid A is a natural product that can be found in Leontopodium leontopodioides?(Willd.) Beauverd.
    Leontopodic acid A