2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3819):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-105439A
    Clofilium phosphate
    Clofilium phosphate (LY 150378) is an antiarrhythmic/antifibrillatory agent. Clofilium phosphate significantly prolongs the action potential duration and effective refractory period of canine cardiac Purkinje fibers, increases the ventricular fibrillation threshold, reduces the risk of reentrant arrhythmias, and enables spontaneous conversion of some ventricular fibrillation episodes to sinus rhythm. Clofilium phosphate is applicable to research related to ventricular fibrillation, arrhythmias, and ventricular tachyarrhythmias.
    Clofilium phosphate
  • HY-W725182
    3,4-Dichloro-α-pyrrolidinoisohexanophenone hydrochloride
    3,4-Dichloro-α-pyrrolidinoisohexanophenone (3,4-Dichloro-α-PiHP) hydrochloride is an analogue of a psychoactive substance.
    3,4-Dichloro-α-pyrrolidinoisohexanophenone hydrochloride
  • HY-138104
    SL-164
    SL-164 is a quinazolinone. SL-164 has sedative properties.
    SL-164
  • HY-169089A
    RP-182-PEG3-K(palmitic acid)-NH2 TFA
    RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts.
    RP-182-PEG3-K(palmitic acid)-NH2 TFA
  • HY-N17143
    6β-Hydroxy-7-epi-α-cyperone
    6β-Hydroxy-7-epi-α-cyperone is a natural sesquiterpene.
    6β-Hydroxy-7-epi-α-cyperone
  • HY-N17880
    Monbarbatain C
    Monbarbatain C is a biphenanthrene compound found in the tubers of Monomeria barbata Lindl. Monbarbatain C induces cytotoxic activity against liver carcinoma and promyelocytic leukaemia cells in vitro. Monbarbatain C mediates DPPH radical scavenging activity in vitro. Monbarbatain C can be used for the research of liver carcinoma, promyelocytic leukaemia, ovarian carcinoma, and epidermoid carcinoma.
    Monbarbatain C
  • HY-N17086
    (3R)-Hydroxyibogaine
    (3R)-Hydroxyibogaine is a natural alkaloid.
    (3R)-Hydroxyibogaine
  • HY-145492
    Δ7(Z)-C14-HSL
    Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes.
    Δ7(Z)-C14-HSL
  • HY-130333
    Tetrahydrohomofolic acid
    Tetrahydrohomofolic acid is an active compound.
    Tetrahydrohomofolic acid
  • HY-N17019
    Mckeanianone B
    Mckeanianone B is a natural xanthone.
    Mckeanianone B
  • HY-163545
    Tc-Me2P
    Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues.
    Tc-Me2P
  • HY-N16955
    22β-Hydroxy-3-oxoolean-12-en-29-oic acid
    22β-Hydroxy-3-oxoolean-12-en-29-oic acid is a natural triterpene.
    22β-Hydroxy-3-oxoolean-12-en-29-oic acid
  • HY-140103
    Azidoethyl-SS-ethylalcohol
    Azidoethyl-SS-ethylalcohol is an active compound.
    Azidoethyl-SS-ethylalcohol
  • HY-N13825
    2-Ethyl-3-methylmaleimide N-β-D-glucopyranoside
    2-Ethyl-3-methylmaleimide N-β-D-glucopyranoside is a natural alkaloid.
    2-Ethyl-3-methylmaleimide N-β-D-glucopyranoside
  • HY-124908
    HT1042
    HT1042 is an active compound.
    HT1042
  • HY-149554
    17-Phenyl trinor Prostaglandin F2α dimethyl amide
    17-Phenyl trinor Prostaglandin F2α dimethyl amide (Bimatoprost dimethyl amide), a 1-OH cyclopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) derivative, is a smooth muscle relaxant. 17-Phenyl trinor Prostaglandin F2α dimethyl amide has the potential for glaucoma research.
    17-Phenyl trinor Prostaglandin F2α dimethyl amide
  • HY-114813
    KHG26693
    KHG26693 is a thiazole derivative with anti-inflammatory and antioxidant properties. KHG26693 normalizes disturbed glucose metabolism by enhancing glucose utilization and decreasing liver glucose production via insulin release. KHG26693 is promising for research of diabetes.
    KHG26693
  • HY-N17629
    13'-Carboxy-α-tocopherol
    13'-Carboxy-α-tocopherol is a vitamin E derivative and antiproliferative agent. 13'-Carboxy-α-tocopherol inhibits proliferation of glioma cancer cells. 13'-Carboxy-α-tocopherol can be used for the research of glioma.
    13'-Carboxy-α-tocopherol
  • HY-154916
    13-O-Desmethyl tacrolimus
    13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the main metabolite of Tacrolimus (HY-13756). 13-O-Desmethyl tacrolimus has a weak immunosuppressive activity. 13-O-Desmethyl tacrolimus is mainly used in the research on monitoring Tacrolimus (HY-13756) by monitoring the ratio of 13-DMT/Tacrolimus.
    13-O-Desmethyl tacrolimus
  • HY-137219
    Δ12(E)-Prostaglandin D2
    Δ12(E)-Prostaglandin D2 is a derivative of Prostaglandin D2 (HY-101988). Prostaglandin D2 is one of the major Prostaglandins actively produced in the brain of various mammals.
    Δ12(E)-Prostaglandin D2