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  3. Drug Derivative
  4. Monbarbatain C

Monbarbatain C is a biphenanthrene compound found in the tubers of Monomeria barbata Lindl. Monbarbatain C induces cytotoxic activity against liver carcinoma and promyelocytic leukaemia cells in vitro. Monbarbatain C mediates DPPH radical scavenging activity in vitro. Monbarbatain C can be used for the research of liver carcinoma, promyelocytic leukaemia, ovarian carcinoma, and epidermoid carcinoma.

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Monbarbatain C

Monbarbatain C Chemical Structure

CAS No. : 1334310-62-1

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Monbarbatain C Related Antibodies

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Description

Monbarbatain C is a biphenanthrene compound found in the tubers of Monomeria barbata Lindl. Monbarbatain C induces cytotoxic activity against liver carcinoma and promyelocytic leukaemia cells in vitro. Monbarbatain C mediates DPPH radical scavenging activity in vitro. Monbarbatain C can be used for the research of liver carcinoma, promyelocytic leukaemia, ovarian carcinoma, and epidermoid carcinoma[1].

In Vitro

Monbarbatain C (compound 3) exhibits significant cytotoxic activity against the HepG-2 and HL-60 cell lines, with the strongest activity against HepG-2 cells (IC50 = 5.80 μM), an IC50 of 10.6 μM against HL-60 cells, and moderate activity against Skov-3 and A431 cells[1].
Monbarbatain C shows considerable DPPH radical scavenging activity with an IC50 of 9.42 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Monbarbatain C Related Antibodies
Molecular Weight

480.51

Formula

C30H24O6
CAS No.
SMILES

OC1=CC=C2C(C=CC3=C(C4=C(O)C=C(CCC5=CC(OC)=CC(O)=C65)C6=C4)C(OC)=CC(O)=C32)=C1
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Monbarbatain C Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monbarbatain C1334310-62-1Drug DerivativeDrug derivativepromyelocytic leukaemia cellsHepG-2DPPH radicalHL-60 cell linesepidermoid carcinomaA431 cellsliver carcinomaovarian carcinomaSkov-3Monomeria barbata Lindl.Inhibitorinhibitorinhibit

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