2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17030
    Daphnenone
    Daphnenone is a natural phenolic compound.
    Daphnenone
  • HY-N18044
    Toosendanal
    Toosendanal is a limonoid compound present in the fruits of Melia toosendan Sieb. et al..
    Toosendanal
  • HY-N17095
    6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one
    6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one is a natural sesquiterpene.
    6-(4-Hydroxyphenyl)-2-methylhept-2-en-4-one
  • HY-119268R
    Thiosildenafil (Standard)
    Thiosildenafil (Standard) is the analytical standard of Thiosildenafil. This product is intended for research and analytical applications. Thiosildenafil, a Sildenafil (HY-15025) analogue, is a compound found in health supplement.
    Thiosildenafil (Standard)
  • HY-177548
    Fmoc-Val-Cit-PAB-Exatecan
    Fmoc-Val-Cit-PAB-Exatecan is a Drug-linker conjugate for ADC. Fmoc-Val-Cit-PAB-Exatecan contains the ADC linker (Fmoc-Val-Cit-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631).
    Fmoc-Val-Cit-PAB-Exatecan
  • HY-N17975
    (Z)-6,7-Epoxyligustilide
    (Z)-6,7-Epoxyligustilide (Compound 8) is a Phthalide (HY-W015820) derivative found in the rhizomes of Ligusticum wallichii.
    (Z)-6,7-Epoxyligustilide
  • HY-N17232
    5α,6α-Epoxyergosta-8,22-diene-3β,7α-diol
    5α,6α-Epoxyergosta-8,22-diene-3β,7α-diol is a natural steroid.
    5α,6α-Epoxyergosta-8,22-diene-3β,7α-diol
  • HY-N19877
    Neokadsuranic acid B
    Neokadsuranic acid B is a 14 (13→12)-seco-lanostane-type triterpenoid acid that exists in the stems of Kadsura longipedunculata and Radix Aconiti Lateralis Preparata. It has high binding affinity for PTGS2 (COX-2). Neokadsuranic acid B shows promise for research into rheumatoid arthritis.
    Neokadsuranic acid B
  • HY-N17098
    (1R,4S)-Epidioxybisabola-2,10-dien-9-one
    (1R,4S)-Epidioxybisabola-2,10-dien-9-one is a natural sesquiterpene.
    (1R,4S)-Epidioxybisabola-2,10-dien-9-one
  • HY-W267459
    2,3-Diphenylmaleic anhydride
    		98.0%
    2,3-Diphenylmaleic anhydride is an analogue of cis-Stilbene.
    2,3-Diphenylmaleic anhydride
  • HY-169122
    LLC1
    LLC1 is an Amiloride (HY-B0285) derivative with cytotoxicity against breast cancer cells, particularly those resistant to treatment. The IC50 values of LLC1 for MCF7, MCF7 MX-100, MCF7 TS, MCF7 TR-1, and MCF7 TR-5 are 13, 12, 25, 26, and 19 mM, respectively. LLC1 shows potential for research in the field of cancer therapy.
    LLC1
  • HY-N17053
    (E)-α-Atlantone
    (E)-α-Atlantone is a natural sesquiterpene.
    (E)-α-Atlantone
  • HY-N1632
    1-Isomangostin hydrate
    1-Isomangostin hydrate is a semi-synthetic cyclized xanthone derivative of α-mangostin (HY-N0328), exhibiting weak cytotoxicity against HT-29 human colon cancer cells (ED50 > 20 μM). 1-Isomangostin hydrate can be used in research on colon cancer and other tumors. The natural precursor of 1-isomangostin hydrate, α-mangostin, is derived from the stem of Cratoxylum cochinchinense (a plant of the Cratoxylum genus in the Clusiaceae family).
    1-Isomangostin hydrate
  • HY-165005A
    (±)14(15)-EET Methyl ester
    (±) 14 (15)-EET Methyl ester (Compound 14,15-EET-Me) is a 14,15-EET (HY-113489) analog and vasodilatory agonist. (±) 14 (15)-EET Methyl ester induces relaxation of precontracted bovine coronary arteries.
    (±)14(15)-EET Methyl ester
  • HY-W591818
    Sunitinib carboxylic acid
    Sunitinib carboxylic acid is a carboxylic acid metabolite of Sunitinib (HY-10255A). Sunitinib is a multi-target tyrosine kinase inhibitor, mainly used to inhibit malignant tumors such as gastrointestinal stromal tumors, renal cell carcinoma, and pancreatic neuroendocrine tumors.
    Sunitinib carboxylic acid
  • HY-N3124
    Osthenone
    Osthenone is a natural coumarin.
    Osthenone
  • HY-113942R
    Cycloate (Standard)
    Cycloate (Standard) is the analytical standard of Cycloate. This product is intended for research and analytical applications. Cycloate is an active compound.
    Cycloate (Standard)
  • HY-118564
    SB209995
    SB209995 is an active compound.
    SB209995
  • HY-115720
    Betulinic acid derivative-1
    Betulinic acid derivative-1 exhibits distinguished activities on inhibiting osteoclast (OC) differentiation with an IC50 value of 1.86 μM.
    Betulinic acid derivative-1
  • HY-N17288
    Myrrhterpenoid G
    Myrrhterpenoid G is a natural product that can be found in Commiphora myrrha?(Nees) Engl..
    Myrrhterpenoid G