2. Signaling Pathways
  3. Others
  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0532
    N-[5-2-[Azo]phenyl]acetamide
    N-[5-2-[Azo]phenyl]acetamide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    N-[5-2-[Azo]phenyl]acetamide
  • HY-138152
    Z-D-Arg-Gly-Arg-pNA dihydrochloride
    Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate.
    Z-D-Arg-Gly-Arg-pNA dihydrochloride
  • HY-D3186
    HMRef-βGal
    HMRef-βGal is a fluorescent probe and a substrate responsive to β-galactosidase (β-galactosidase) (Ex/Em=498 nm/505-600 nm). After being cleaved by β-galactosidase, HMRef-βGal triggers significant fluorescence enhancement via intramolecular spirocyclic function regulation. HMRef-βGal generates bright fluorescence in cancer cells with elevated β-galactosidase activity, enabling visualization of tiny peritoneal metastases in mouse models. HMRef-βGal exhibits low in vitro cytotoxicity and low acute in vivo toxicity in mice. HMRef-βGal can be used for preclinical fluorescence-guided diagnosis and cytoreductive surgery of peritoneal metastases, including compatibility with real-time naked-eye detection and endoscopic imaging, as well as for studies related to peritoneal metastases of ovarian cancer.
    HMRef-βGal
  • HY-177621D
    Cy3 labled Cevolisiran sodium
    Cy3 labled Cevolisiran sodium is a Cy3 labled Cevolisiran sodium.
    Cy3 labled Cevolisiran sodium
  • HY-D2030
    ATTO 514 streptavidin
    ATTO 514 streptavidin is a streptavidin derivative of ATTO 514, it can label protein or antibody, the maximum excitation/emission wavelength: 511/531 nm.
    ATTO 514 streptavidin
  • HY-D1186
    2-Aza-ε-adenosine
    2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    2-Aza-ε-adenosine
  • HY-D3197
    CDg16
    CDg16 is a selective fluorescent dye targeting SLC18B1 (λabs/λem=458/544 nm) that is actively transported into lysosomal vesicles of activated macrophages independent of the endocytic pathway. CDg16 enables highly specific vesicle localization in live cells. CDg16 exhibits no cytotoxicity and accurately distinguishes activated M1 and M2 subsets from different origins. CDg16 shows low background staining in non-activated cells and normal organs, making it suitable for time-lapse imaging. In preclinical animal models of inflammatory sites, atherosclerotic plaques and liver inflammation, CDg16 allows visualization of activated macrophages. CDg16 can be used to study inflammation-related diseases and atherosclerosis.
    CDg16
  • HY-P4367
    TRH-AMC
    TRH-AMC is a fluorogenic substrate used in a coupled assay for thyrotropin-releasing hormone(TRH)-degrading ectoenzyme.
    TRH-AMC
  • HY-D2058
    ATTO 700 NHS ester
    ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
    ATTO 700 NHS ester
  • HY-D0377
    Solvaperm Green G
    Solvaperm Green G is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Solvaperm Green G
  • HY-P6285
    Z-TPE-2DEVD
    Z-TPE-2DEVD is a specific probe for caspase-3.
    Z-TPE-2DEVD
  • HY-D1828
    Vari Fluor 640 Carboxylic acid（free acid）
    Vari Fluor 640 Carboxylic acid (VF 640 Carboxylic acid) free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivatives are unactivated labeled fluorescent dyes for protein, antibody, and polysaccharide labeling that require carboxylic acid activation for use.
    Vari Fluor 640 Carboxylic acid（free acid）
  • HY-D3151
    RHBCu
    RHBCu is a rhodamine-based azophenol derivative and a fluorescent indicator for Cu2+. RHBCu exhibits high selectivity for Cu2+ ions and enables fluorescent imaging of Cu2+ in cancer cells.
    RHBCu
  • HY-W320397
    4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan
    4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.
    4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan
  • HY-D2883A
    RB-PEG600-SH
    RB-PEG600-SH (Rhodamine B-PEG600-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm).
    RB-PEG600-SH
  • HY-D2978
    MR2-cy5
    MR2-cy5 is a fluorescent agent. MR2-cy5 is highly specific to CD206. MR2-cy5 can track CD206+ macrophages.
    MR2-cy5
  • HY-177632D
    Cy3 labled Frenlosirsen sodium
    Cy3 labled Frenlosirsen sodium is a Cy3 labled Frenlosirsen sodium.
    Cy3 labled Frenlosirsen sodium
  • HY-D1920
    ATTO 390 azide
    ATTO 390 azide is an azide derivative of ATTO 390 with excitation/emission maxima at 390/476 nm. ATTO 390 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    ATTO 390 azide
  • HY-151712
    Sulfo-Cy5-Methyltetrazine
    Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.
    Sulfo-Cy5-Methyltetrazine
  • HY-D0711S2
    Indocyanine green-d7
    Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.
    Indocyanine green-d<sub>7</sub>
Cat. No. Product Name / Synonyms Application Reactivity