RHBCu
RHBCu is a rhodamine-based azophenol derivative and a fluorescent indicator for Cu2+. RHBCu exhibits high selectivity for Cu2+ ions and enables fluorescent imaging of Cu2+ in cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 1698054-83-9
- Formula: C41H40N6O3
- Molecular Weight:664.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
RHBCu (1 μM; <30 s) forms a 1:1 complex with Cu2+ in an ethanol-water buffer (pH 7.14), induces a 14-fold fluorescence enhancement at 575 nm, and reaches a detection limit of 7.2×10-7 mol/L[1].
RHBCu (10 μM; 30 min) is cell-permeable and can detect Cu2+ in living HeLa cells; a strong fluorescent signal is generated when the cells are treated and then exposed to 20 μM Cu2+[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1698054-83-9
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Molecular Weight 664.79
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Formula C41H40N6O3
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SMILES
CCN(C1=CC2=C(C3(C4=C(C(N3/N=C/C5=CC(/N=N/C6=CC=CC=C6)=CC=C5O)=O)C=CC=C4)C7=C(O2)C=C(C=C7)N(CC)CC)C=C1)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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