2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-173532
    2-Methylthio TNP-ITP tetrasodium
    2-Methylthio TNP-ITP (2-Methylthio TNP-Inosine 5'-triphosphate) tetrasodium is a fluorescent derivative of inosine triphosphate (ITP) with a TNP (2,4,6-trinitrophenyl) fluorophore.
    2-Methylthio TNP-ITP tetrasodium
  • HY-D145729F
    FAM-Danvatirsen
    FAM-Danvatirsen is a FAM-labeled Danvatirsen (HY-145729). Danvatirsen is an antisense oligonucleotide targeting STAT3 that can be used in the study of cancer.
    FAM-Danvatirsen
  • HY-D1463
    Nile Blue Methacrylamide
    Nile Blue Methacrylamide is a pH-responsive probe. Nile Blue Methacrylamide exhibits pH-sensitive absorption and fluorescence emission in the physiological pH range, with spectral shifts occurring between acidic and near-physiological pH conditions. (Ex/Em = 590/670-700 nm)
    Nile Blue Methacrylamide
  • HY-147114
    3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin
    3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm.
    3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin
  • HY-D3226
    Zinc(II) probe-1
    Zinc (II) probe-1 (Compound DNP) is a dual-color Fluorescent probe that can simultaneously monitor Zn2+ and H+. Upon interaction with Zn2+, Zinc (II) probe-1 produces bright blue fluorescence (excitation wavelength: 405 nm; blue channel wavelength: 420-500 nm). Upon interaction with H+, Zinc (II) probe-1 exhibits red fluorescence (excitation wavelength: 561 nm; red channel emission wavelength: 630-730 nm). Zinc (II) probe-1 can be used in studies related to depression.
    Zinc(II) probe-1
  • HY-D2094
    PerCP Maleimide
    PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes.
    PerCP Maleimide
  • HY-D2020
    ATTO 665 maleimid
    ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
    ATTO 665 maleimid
  • HY-108753E
    Cy3 labled Eteplirsen sodium
    Cy3 labled Eteplirsen sodium is a Cy3 labled Eteplirsen sodium.
    Cy3 labled Eteplirsen sodium
  • HY-D2800A
    FITC-PEG1000-MAL
    FITC-PEG1000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG1000-MAL can be used for fluorescent labeling and imaging.
    FITC-PEG1000-MAL
  • HY-D1585
    BODIPY TR methyl ester
    BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo.
    BODIPY TR methyl ester
  • HY-D2158
    Cy5-PEG7-SCO
    Cy5-PEG7-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
    Cy5-PEG7-SCO
  • HY-D1544
    Uniblue A sodium
    Uniblue A sodium is a reactive protein stain that can be used in the covalent pre-gel staining of the protein (Ex=594 nM).
    Uniblue A sodium
  • HY-D2274
    EZH2-AF647
    EZH2-AF647 is a fluorescent probe derived from UNC2239 that improves receptor TR-FRET properties by using Alexa 647 dye.
    EZH2-AF647
  • HY-N15824
    Cyanine 3.5 azide
    Cyanine 3.5 azide is a cyanine dye functionalized with an azide. Cyanine 3.5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 591/604 nm).
    Cyanine 3.5 azide
  • HY-D2888A
    RB-PEG600-FA
    RB-PEG600-FA (Rhodamine B-PEG600-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG600-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm).
    RB-PEG600-FA
  • HY-158616
    4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one
    4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.
    4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one
  • HY-D1179
    Solvent violet 38
    Solvent violet 38 is a violet dye. Its series of products, such as Solvent orange 60 (HY-D1177), has been used in dyeing applications of plastic materials.
    Solvent violet 38
  • HY-D3036
    5-(6)-Carboxy SNAFL-1 SE
    5-(6)-Carboxy SNAFL-1 SE is an amine-reactive succinimidyl ester pH indicator. 5-(6)-Carboxy SNAFL-1 SE can be readily conjugated to peptides, antibodies and other amino-containing molecules such as amino-modified oligos. 5-(6)-Carboxy SNAFL-1 SE can be used for measurement of pH changes between 7-8 (Ex/Em = 490/513 nm).
    5-(6)-Carboxy SNAFL-1 SE
  • HY-D3329
    SMCC Activatrd APC
    SMCC Activatrd APC is a pre-activated fluorescent labeling reagent (Ex/Em = 652/662 nm) that has been pre-modified with the heterodially crosslinking agent SMCC (HY-42360) using alloxanthin protein (Allophycocyanin, APC).
    SMCC Activatrd APC
  • HY-D3375
    RAPID DiI
    RAPID DiI is a cyanine dye with orange-red fluorescenc (EX≈550 nm; Em≈565 nm). RAPID DiI is a lipophilic dye that labels cell membranes by inserting its two long hydrocarbon (C18 carbon) chains into the lipid bilayer. RAPID DiI is weakly fluorescent until incorporated into membranes. RAPID DiI diffuses laterally to stain the entire cell, allowing it to be used as an anterograde and retrograde tracer of neurons.
    RAPID DiI
Cat. No. Product Name / Synonyms Application Reactivity