2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. 상품명 효과 Purity Chemical Structure
  • HY-D0534
    2-4-(2-Cyanoethyl)(2-phenylethyl)aminophenylazo-5-nitrobenzonitrile
    2-4-(2-Cyanoethyl)(2-phenylethyl)aminophenylazo-5-nitrobenzonitrile is a storage-stable, fluid, nonagglomerating dispersions of azo dye.
    2-4-(2-Cyanoethyl)(2-phenylethyl)aminophenylazo-5-nitrobenzonitrile
  • HY-150175
    HKSOX-1
    HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2•−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2•−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2•− roles in inflammation, mitochondrial stress, and other physiological processes.
    HKSOX-1
  • HY-P4403
    Z-DEVD-R110
    Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore.
    Z-DEVD-R110
  • HY-D2964
    NBzF-BG
    NBzF-BG is a novel H2O2-specific fluorescent probe. NBzF-BG shows visible absorption centered at 505 nm and weak fluorescence with an emission maximum at 525 nm. NBzF-BG is covalently and selectively conjugated with the SNAP-tag protein, leading to formation of the fluorophore-protein conjugate (SNAP-NBzF). SNAP-NBzF rapidly reacts with H2O2 and thereby shows an enhancement in fluorescence.
    NBzF-BG
  • HY-D2145
    Cy5-PEG2-TCO4
    Cy5-PEG2-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
    Cy5-PEG2-TCO4
  • HY-177638D
    Cy3 labled ISIS 1082 sodium
    Cy3 labled ISIS 1082 sodium is a Cy3 labled ISIS 1082 sodium.
    Cy3 labled ISIS 1082 sodium
  • HY-D2341
    6FC-GABA-Taxol
    6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors.
    6FC-GABA-Taxol
  • HY-123275C
    H-D-Phe-Pip-Arg-pNA dihydrochloride
    H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform.
    H-D-Phe-Pip-Arg-pNA dihydrochloride
  • HY-W331502
    Chlorophenol Red sodium
    Chlorophenol Red sodium is a pH indicator.
    Chlorophenol Red sodium
  • HY-D2048
    ATTO 532 streptavidin
    ATTO 532 streptavidin is a streptavidin derivative of ATTO 532, it can label protein or antibody, the maximum excitation/emission wavelength: 532/552 nm.
    ATTO 532 streptavidin
  • HY-D1155
    Pigment red 176
    Pigment Red 176 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.
    Pigment red 176
  • HY-132593E
    Cy3 labled Rovanersen sodium
    Cy3 labled Rovanersen sodium is a Cy3 labled Rovanersen sodium.
    Cy3 labled Rovanersen sodium
  • HY-177670D
    Cy3 labled Zintevir sodium
    Cy3 labled Zintevir sodium is a Cy3 labled Zintevir sodium.
    Cy3 labled Zintevir sodium
  • HY-D2486
    Sulfo Cy3 bis NHS ester
    Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    Sulfo Cy3 bis NHS ester
  • HY-D1365A
    Sulfo-Cy3(Me)COOH TEA
    Sulfo-Cy3(Me)COOH TEA is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm).
    Sulfo-Cy3(Me)COOH TEA
  • HY-D1641
    5,5'-Dimethyl BAPTA tetrapotassium
    5,5'-Dimethyl BAPTA tetrapotassium is a water-soluble, extracellular membrane metal chelator with relative selectivity for calcium ions.
    5,5'-Dimethyl BAPTA tetrapotassium
  • HY-D1433
    FITC-C6-LEHD-FMK
    FITC-C6-LEHD-FMK, a fluorescently labeled caspase-9 inhibitor, can be used for detection of active caspase-9 in mammalian cells undergoing apoptosis. FITC-C6-LEHD-FMK provides a convenient means for sensitive detection of activated caspase-9 in living cells. Z-LEHD-FMK is a specific caspase-9 inhibitor.
    FITC-C6-LEHD-FMK
  • HY-145385
    Coelenteramide
    Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent.
    Coelenteramide
  • HY-D1827
    Vari Fluor 660 Carboxylic acid（free acid）
    Vari Fluor 660 Carboxylic acid (VF 660 Carboxylic acid) free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivatives are unactivated labeled fluorescent dyes for protein, antibody, and polysaccharide labeling that require carboxylic acid activation for use.
    Vari Fluor 660 Carboxylic acid（free acid）
  • HY-D1589
    8-Methyl-2,6-diphenylethynyl-BODIPY 505/515
    8-Methyl-2,6-diphenylethynyl-BODIPY 505/515 is a fluorochrome.
    8-Methyl-2,6-diphenylethynyl-BODIPY 505/515
Cat. No. 상품명 / Synonyms Application Reactivity