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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Art. -Nr. Produktname Wirkung Reinheit Chemical Structure
  • HY-D0100
    Fluorescein-diacetate-5-isothiocyanat
    Fluorescein-diacetate-5-isothiocyanat is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
    Fluorescein-diacetate-5-isothiocyanat
  • HY-D2101
    TAMRA-PEG3-NH2
    TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
    TAMRA-PEG3-NH2
  • HY-D2610
    ICG PEG2000 DSPE
    ICG PEG2000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG2000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
    ICG PEG2000 DSPE
  • HY-W440913
    DSPE-PEG5000-Cy5
    DSPE-PEG-Cy5, MW 5000 is a fluorescently labeled PEGylated phospholipid with a molecular weight of 5000 Da. After intravenous injection, DSPE-PEG-Cy5, MW 5000 shows only extremely low fluorescence accumulation at tumor sites in orthotopic tumor-bearing mice, and can be used as a negative control for evaluating tumor accumulation of nanoparticles. DSPE-PEG-Cy5, MW 5000 can serve as a fluorescent marker to prepare Cy5-labeled NPs-DPPA and NPs-DPPA (C3F8) for pharmacokinetic and biodistribution studies in mice. DSPE-PEG-Cy5, MW 5000 is widely applicable to research in fields related to triple-negative breast cancer, hepatocellular carcinoma and so on.
    DSPE-PEG5000-Cy5
  • HY-132270
    FAM amine, 5-isomer
    FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.
    FAM amine, 5-isomer
  • HY-D2672
    Cy7 HA (MW 3000)
    Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
    Cy7 HA (MW 3000)
  • HY-D2741
    MB 488 NHS ester
    MB 488 NHS ester is a fluroescent agent with a terminal NHS ester group. MB 488 NHS ester is a green fluorescent, very hydrophilic dye molecule that has a maximal absorption of 501 nm and emission at 524 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    MB 488 NHS ester
  • HY-158828C
    Cy3 labled SSO111 sodium
    Cy3 labled SSO111 sodium is a Cy3 labled SSO111 sodium.
    Cy3 labled SSO111 sodium
  • HY-W998658
    BODIPY 564/570
    BODIPY 564/570 is a fluorescent dye that can be used in labeling superparamagnetic nanoparticles (MNPs). BODIPY 564/570 exhibits a maximal excitation wavelength of 564 nm and a maximal emission wavelength of 570 nm.
    BODIPY 564/570
  • HY-D2594
    Cy7.5-PEG3400-DSPE
    Cy7.5-PEG3400-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
    Cy7.5-PEG3400-DSPE
  • HY-D0558
    Disperse blue 165
    Disperse blue 165 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Disperse blue 165
  • HY-D0540
    Direct orange 118
    Direct orange 118 is a good dyeing agent for cotton fabrics.
    Direct orange 118
  • HY-D2628
    Cy3 HA (MW 500000)
    Cy3 HA (MW 500000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
    Cy3 HA (MW 500000)
  • HY-D2851B
    FITC-PEG5000-CHOL
    FITC-PEG5000-CHOL is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG5000-CHOL is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em=488/525 nm).
    FITC-PEG5000-CHOL
  • HY-D0406
    C.I. Basic yellow 37
    C.I. Basic yellow 37 is an alkaline dye that can be removed from aqueous solutions in intermittent adsorption systems using tree ferns as biosorbents.
    C.I. Basic yellow 37
  • HY-148410H
    Cy3 labled Zorevunersen sodium
    Cy3 labled Zorevunersen sodium is a Cy3 labled Zorevunersen sodium.
    Cy3 labled Zorevunersen sodium
  • HY-D0669
    Reactive orange 4
    Reactive orange 4 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 4
  • HY-123696
    CDy9
    CDy9 is a highly selective fluorescent probe. CDy9 can be used to detect mouse embryonic stem cells. ( λ exc. / λ em.：563 nm/578 nm).
    CDy9
  • HY-D2627
    Cy3 HA (MW 200000)
    Cy3 HA (MW 200000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
    Cy3 HA (MW 200000)
  • HY-D2324
    EE-Flipper 33
    EE-Flipper 33 is a Flipper probe designed to evaluate the mechanism of early endocytosis. EE-Flipper has a pKa value of 10.6 and is capable of tracking approximately 70% of early endosomes (EE) in live cells. Furthermore, EE-Flipper 33 can also label the Golgi apparatus in live cells with an internal pH ranging from 6.0 to 6.7.
    EE-Flipper 33
Art. -Nr. Produktname / Synonyms Application Reactivity