2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-158821D
    Cy3 labled ISTH0036 sodium
    Cy3 labled ISTH0036 sodium is a Cy3 labled ISTH0036 sodium (HY-158821A). ISTH0036 sodium is a phosphorothioate LNA-modified antisense oligonucleotide gapmer that selectively targets and downregulates TGF-β2 mRNA. ISTH0036 sodium suppresses TGF-β2 expression, reduces choroidal neovascularization and vascular leakage, inhibits fibrosis, blocks epithelial-to-mesenchymal transition, and inhibits angiogenesis while promoting bleb survival. ISTH0036 sodium exhibits long-lasting, dose-dependent ocular tissue distribution and target engagement in rabbit and non-human primate eyes. ISTH0036 sodium can be used for the study of various ocular disorders, such as glaucoma and neovascular retinal diseases.
    Cy3 labled ISTH0036 sodium
  • HY-D2740
    ROX azide, 6-isomer
    ROX azide, 6-isomer is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.
    ROX azide, 6-isomer
  • HY-158821C
    FAM labled ISTH0036 sodium
    FAM labled ISTH0036 sodiumis a FAM labled ISTH0036 sodium (HY-158821A). ISTH0036 sodium is a phosphorothioate LNA-modified antisense oligonucleotide gapmer that selectively targets and downregulates TGF-β2 mRNA. ISTH0036 sodium suppresses TGF-β2 expression, reduces choroidal neovascularization and vascular leakage, inhibits fibrosis, blocks epithelial-to-mesenchymal transition, and inhibits angiogenesis while promoting bleb survival. ISTH0036 sodium exhibits long-lasting, dose-dependent ocular tissue distribution and target engagement in rabbit and non-human primate eyes. ISTH0036 sodium can be used for the study of various ocular disorders, such as glaucoma and neovascular retinal diseases.
    FAM labled ISTH0036 sodium
  • HY-W800769
    BP Fluor 532 azide plus
    BP Fluor 532 Azide Plus is a fluroescent agent with a terminal azide group. The fluroescent compound has a max absorption at 532 nm and emission at 554 nm. The BP Fluor 532 Azide Plus was designed with a copper-chelating system within its structure, enabling the formation of strong, active copper complexes that act as both reactant and catalyst in CuAAC reactions.
    BP Fluor 532 azide plus
  • HY-A0216
    Hydroxystilbamidine diisethionate
    Hydroxystilbamidine diisethionate, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine diisethionate is a retrograde fluorescent tracer and histochemical stain.
    Hydroxystilbamidine diisethionate
  • HY-D2225
    IR-34
    IR-34 is an indole cyanine dye.
    IR-34
  • HY-D2880
    Sulfo-Cyanine5 DBCO
    		98.02%
    Sulfo-Cyanine5 DBCO is a near-infrared red (NIR) fluorescent dye. Sulfo-Cyanine5 DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em =646/670 nm).
    Sulfo-Cyanine5 DBCO
  • HY-151728
    Trisulfo-Cy3-Alkyne
    Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only. Trisulfo-Cy3-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Trisulfo-Cy3-Alkyne
  • HY-D2736
    BP Light 800 NHS ester
    BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
    BP Light 800 NHS ester
  • HY-D2603
    ICG PEG10000 NH2
    ICG PEG10000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG10000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
    ICG PEG10000 NH2
  • HY-W927376
    Boc-Val-Arg-AMC
    Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples.
    Boc-Val-Arg-AMC
  • HY-D0481
    C.I. Acid orange 67
    C.I. Acid orange 67 is an acidic orange-yellow dye that can be adsorbed and removed by bentone.
    C.I. Acid orange 67
  • HY-D2848A
    Chitosan-Cy5.5 (MW 55000)
    Chitosan-Cy5.5 (MW 55000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 55000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm).
    Chitosan-Cy5.5 (MW 55000)
  • HY-D0316
    Disperse red 167:1
    Disperse red 167:1 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
    Disperse red 167:1
  • HY-W713888
    Aniline blue diammonium
    Aniline blue diammonium is a component of commonly used polychrome stains. Aniline blue diammonium is used to stain collagen fibers in tissue sections using Masson′s trichrome protocol for staining multiple components. Collagen is stained blue by this method. The dye is suitable for selective staining of callose in plant specimens and staining histones for assessing nuclear maturity. Aniline blue diammonium is used in Gomori′s one-step trichrome stain and Mallory′s connective tissue stain for tissue including kidney and intestine.
    Aniline blue diammonium
  • HY-W776847
    3-(2-Iodoacetamido)-proxyl
    3-(2-Iodoacetamido)-proxyl serves as a free radical spin probe employed in spin labeling techniques, which facilitate the exploration of the dynamic interactions among molecules, proteins, lipids, and cell membranes.
    3-(2-Iodoacetamido)-proxyl
  • HY-101900R
    Nile Blue A sulfate (Standard)
    Nile Blue A sulfate (Standard) is the analytical standard of Nile Blue A sulfate (HY-101900). This product is intended for research and analytical applications. Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor.
    Nile Blue A sulfate (Standard)
  • HY-D2625
    Cy3 HA (MW 50000)
    Cy3 HA (MW 50000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
    Cy3 HA (MW 50000)
  • HY-D0543
    Pigment yellow 151
    Pigment yellow 151 is a disazomethine dye with solid-state fluorescence.a biologically active chemical.
    Pigment yellow 151
  • HY-W749072
    BP Fluor 568 NHS ester
    BP Fluor 568 NHS ester is an amine-reactive, orange fluorescent dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules (Ex/Em: 578 nm/602 nm).
    BP Fluor 568 NHS ester
Cat. No. Product Name / Synonyms Application Reactivity