Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Verwandte Produkte (10875):

Art. -Nr.	Produktname	Wirkung	Reinheit	Chemical Structure

HY-W011817S

1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d₃		98%
1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d₃ is the deuterium labeled 1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone.

HY-10585S3

Valproic acid-d₄ sodium
Valproic acid-d₄ (sodium) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

HY-W744788

Amitriptylinoxide-d₆
Amitriptylinoxide-d₆ (Equilibrin-d₆) is the deuterium labeled Amitriptylinoxide (HY-107032). Amitriptylinoxide (Equilibrin) is an analogue and metabolite of amitriptyline with similar antidepressant efficacy.

HY-157077S

5-Hydroxysaxagliptin-¹³C,d₂ trifluoroacetate
5-Hydroxysaxagliptin-¹³C,d₂ (TFA) is ¹³C-labeled 5-Hydroxysaxagliptin.

HY-W710742

N,N-Diethylbenzamide-d₅
N,N-Diethylbenzamide-d₅ (Benzoyldiethylamine-d₅) is the deuterium labeled N,N-Diethylbenzamide (HY-124545).

HY-34628S

Tri-O-acetyl-D-glucal-¹³C
3,4,6-Tri-O-acetyl-D-glucal-¹³C is the ¹³C labeled 3,4,6-Tri-O-acetyl-D-glucal.

HY-13716S

Noscapine-¹³C,d₃
Noscapine-¹³C,d₃ is a ¹³C- labeled and deuterated labeled Noscapine. Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier.

HY-146867S

1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d₅ sodium
1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-144199S

5-Hydroxy Saxagliptin-¹³C,d₂ (hydrochloride)
5-Hydroxy Saxagliptin-¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled 5-Hydroxy Saxagliptin.

HY-N0006S

Demethoxycurcumin-d₇
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-W770285

Bisphenol A bis-(β-D-glucuronide)-¹³C₁₂ sodium
Bisphenol A bis-(β-D-glucuronide)-¹³C₁2 sodium is the ¹³C-labeled Bisphenol A bis-(β-D-glucuronide).

HY-W710819

1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d₁₁
1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d₁₁ is the deuterium labeled 2-(1-Hydroxycyclohexyl)-2-(4-methoxyphenyl)acetonitrile (HY-W128231).

HY-N1446S7

Oleic acid-d₁₄
Oleic acid-d₁₄ (9-cis-Octadecenoic acid-d₁₄) is the deuterium labeled Oleic acid-d14.

HY-W707498

Baclofen-d₄-1
Baclofen-d₄-1 is the deuterium labeled Baclofen (HY-B0007). Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research.

HY-137012S

8-iso Prostaglandin F1α-d₉
8-iso Prostaglandin F1α-d₉ is the deuterium labeled 8-iso Prostaglandin F1α.

HY-75954S

2-Hydroxyhexanoic acid-d₃
2-Hydroxyhexanoic acid-d₃ is the deuterium labeled 2-Hydroxyhexanoic acid (HY-75954). 2-Hydroxyhexanoic acid is an endogenous metabolite.

HY-10820AS

Pemetrexed-d₅ disodium
Pemetrexed-d₅ disodium is the deuterium labeled Pemetrexed disodium. Pemetrexed disodium (LY231514 disodium) is an antifolate, the K_is of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

HY-178754S

12-Dipalmitoyl-sn-glycero-3-PS-d₃ ammonium
12-Dipalmitoyl-sn-glycero-3-PS-d₃ ammonium is the deuterium labeled 12-Dipalmitoyl-sn-glycero-3-PS ammonium.

HY-139312S

L-Mannitol-1-¹³C
L-Mannitol-1-¹³C is the ¹³C labeled L-Mannitol. L-mannitol is a compound?can be used for ?the compound sweetener synthesis.

HY-W718361

N-Methylpropan-2-amine hydrochloride-d₇
N-Methylpropan-2-amine hydrochloride-d₇ is the deuterium labeled N-Methylpropan-2-amine hydrochloride (HY-W718354).

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