2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10678):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-I0293S
    Alogliptin impurity 7-d3
    Alogliptin impurity 7-d3 is deuterium labeled (R)-2-((6-(3-((3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile.
    Alogliptin impurity 7-d<sub>3</sub>
  • HY-141926S
    Deoxycholic Acid-3-Sulfate Sodium Salt-d4
    Deoxycholic Acid-3-Sulfate Sodium Salt-d4 is the deuterium labeled Deoxycholic Acid-3-Sulfate Sodium Salt.
    Deoxycholic Acid-3-Sulfate Sodium Salt-d<sub>4</sub>
  • HY-40354S2
    Tofacitinib-13C,d3
    Tofacitinib-13C,d3 (Tasocitinib-13C,d3) is 13C labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
    Tofacitinib-<sup>13</sup>C,d<sub>3</sub>
  • HY-118901S
    Opipramol-d4
    Opipramol-d4 is the deuterium labeled Opipramol.
    Opipramol-d<sub>4</sub>
  • HY-132626S
    N-Desmethyl Tamoxifen-d5
    N-Desmethyl Tamoxifen-d5 is the deuterium labeled N-Desmethyl Tamoxifen.
    N-Desmethyl Tamoxifen-d<sub>5</sub>
  • HY-W753141
    p,p'-DDE-13C12
    p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
    p,p'-DDE-<sup>13</sup>C<sub>12</sub>
  • HY-150544S
    N-Desmethyl selegiline-d5 hydrochloride
    N-Desmethyl Selegiline-dd5 hydrochloride is the deuterium labeled N-Desmethyl Selegiline hydrochloride. N-Desmethyl Selegiline-d5 hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-Desmethyl selegiline-d<sub>5</sub> hydrochloride
  • HY-B0103AS
    (E)-Fluvoxamine-d4 maleate
    (E)-Fluvoxamine-d4 (maleate) is the deuterium labeled (E)-Fluvoxamine maleate[1].
    (E)-Fluvoxamine-d<sub>4</sub> maleate
  • HY-106577S
    Cibenzoline-d4
    Cibenzoline-d4 (Cifenline-d4) is deuterium labeled Cibenzoline. Cibenzoline is a class Ia antiarrhythmic active molecule with low anticholinergic activity. Cibenzoline is a KATP channel inhibitor, acting through the pore forming subunit Kir6.2, with an IC50 of 22.2 μM. Cibenzoline inhibits IKr and IKs currents with IC50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is used in the study of cardiac diseases. In addition, Cibenzoline can induce hypoglycemia.
    Cibenzoline-d<sub>4</sub>
  • HY-P0009S1
    Cetrorelix-d10
    Cetrorelix-d10 (SB-75-d10) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice.
    Cetrorelix-d<sub>10</sub>
  • HY-N7105S
    γ-Decalactone-d7
    γ-Decalactone-d7 is deuterated labeled γ-Decalactone. γ-Decalactone is a natural flavoring substance with the fruity aroma of juicy peaches. γ-Decalactone can be used as a food additive.
    γ-Decalactone-d<sub>7</sub>
  • HY-143848S
    Tadalafil-13C,d3
    Tadalafil-13C,d3 is the deuterium and 13C labeled Tadalafil.
    Tadalafil-<sup>13</sup>C,d<sub>3</sub>
  • HY-150012S2
    N-Lactoyl-phenylalanine-d5
    N-Lactoyl-phenylalanine-d5 (Lac-Phe-d5) is the deuterium labeled N-Lactoyl-phenylalanine (HY-150012). N-Lactoyl-phenylalanine is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-phenylalanine can reduce obesity and improve glucose tolerance.
    N-Lactoyl-phenylalanine-d<sub>5</sub>
  • HY-165640S
    (±)8,9-DiHETrE-d11
    (±)8(9)-DiHET-d11 is deuterium labeled (±)8(9)-DiHET.
    (±)8,9-DiHETrE-d<sub>11</sub>
  • HY-W040193S1
    DSPC-d74
    		99%
    DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
    DSPC-d<sub>74</sub>
  • HY-W355238S
    Sec-butyl butyrate-d2
    Sec-butyl butyrate-d2 is deuterated labeled Sec-butyl butyrate.
    Sec-butyl butyrate-d<sub>2</sub>
  • HY-W754640
    Isopropyl 2-hydroxybenzoate-d7
    Isopropyl 2-hydroxybenzoate-d7 (Salicylic acid isopropyl ester-d7) is deuterium labeled Isopropyl 2-hydroxybenzoate.
    Isopropyl 2-hydroxybenzoate-d<sub>7</sub>
  • HY-B2169S2
    Melperone-d4 hydrochloride
    		99.84%
    Melperone-d4 hydrochloride is the deuterium labeled Melperone hydrochloride (HY-103109). Melperone hydrochloride is a butyrophenone with atypical antipsychotic properties. Melperone hydrochloride is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, respectively. Melperone hydrochloride has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values ​​of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone hydrochloride is also a CYP2D6 inhibitor. Melperone hydrochloride can be used for the study of schizophrenia, and agitation in the elderly.
    Melperone-d<sub>4</sub> hydrochloride
  • HY-W653745
    6-Thioguanine-13C2,15N
    6-Thioguanine-13C2,15N (Thioguanine-13C2,15N) is the 13C and 15N labeled 6-Thioguanine (HY-13765). 6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
    6-Thioguanine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W275481S1
    5-Octyldihydrofuran-2(3H)-one-d4
    5-Octyldihydrofuran-2(3H)-one-d4 is deuterated labeled 5-Octyldihydrofuran-2(3H)-one.
    5-Octyldihydrofuran-2(3H)-one-d<sub>4</sub>