p,p'-DDE-13C12
p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
For research use only. We do not sell to patients.
- CAS No.: 201612-50-2
- Formula: C213C12H8Cl4
- Molecular Weight:329.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 201612-50-2
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Unlabeled Cas 72-55-9
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Molecular Weight 329.94
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Formula C213C12H8Cl4
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SMILES
C(=C(Cl)Cl)([13C]1=[13CH][13CH]=[13C](Cl)[13CH]=[13CH]1)[13C]2=[13CH][13CH]=[13C](Cl)[13CH]=[13CH]2
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Synonyms
4,4'-DDE-13C12; p,p'-Dichlorodiphenyldichloroethylene-13C12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
p,p'-DDE-13C12 Related Classifications
HY-W753141 Related Classifications
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