p,p'-DDE-13C12
p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
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- CAS 番号: 201612-50-2
- 分子式: C213C12H8Cl4
- 分子量:329.94
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 201612-50-2
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非標識Cas 72-55-9
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分子量 329.94
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分子式 C213C12H8Cl4
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SMILES
C(=C(Cl)Cl)([13C]1=[13CH][13CH]=[13C](Cl)[13CH]=[13CH]1)[13C]2=[13CH][13CH]=[13C](Cl)[13CH]=[13CH]2
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別名
4,4'-DDE-13C12; p,p'-Dichlorodiphenyldichloroethylene-13C12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)