72-55-9
Chemical Structure
p,p'-DDE
Synonym(s): 4,4'-DDE; p,p'-Dichlorodiphenyldichloroethylene
- CAS No.: 72-55-9
- Formula:C14H8Cl4
- Molecular Weight:318.03
IUPAC Name: 4,4'-(2,2-dichloroethene-1,1-diyl)bis(chlorobenzene)
InChIKey: UCNVFOCBFJOQAL-UHFFFAOYSA-N
SMILES: Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2
Biological Activity: p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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p,p'-DDE | 99.91% | p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women. | ||||||||||||||||||||
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p,p'-DDE (Standard) | ≥98% | p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women. | ||||||||||||||||||||
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p,p'-DDE-d8 | 99% | p,p'-DDE-d8 is the deuterium labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM. | ||||||||||||||||||||
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p,p'-DDE-13C12 | p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM. | |||||||||||||||||||||
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