Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-157071S

Seliciclib Carboxylic Acid-d₇
Seliciclib Carboxylic Acid-d₇ is deuterium-labeled Seliciclib Carboxylic Acid.

HY-109506S2

(Rac)-DPPC-d₆		98.0%
(Rac)-DPPC-d6 is a deuterated labeled DPPC. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.

HY-P3207S

DLPLTFGGGT-Lys¹³C₆,¹⁵N₂ TFA
DLPLTFGGGT-Lys-13C6,15N2 (TFA) is a deuterated labeled DLPLTFGGGTK.

HY-126050S

(R)-Pantetheine-¹⁵N
(R)-Pantetheine-¹⁵N (Pantetheine-¹⁵N) is the ¹⁵N labeled (R)-Pantetheine (HY-126050). (R)-Pantetheine is the biosynthetic precursor to CoA.

HY-132580S

Tofersen-d₂₇
Tofersen-d₂₇ (BIIB067-d₂₇) is the deuterium labeled Tofersen (HY-132580). Tofersen (BIIB067) is an antisense oligonucleotide and SOD1 mRNA inhibitor with an IC₅₀ of 320 pM. Tofersen mediates RNase H-dependent degradation of SOD1 mRNA to reduce SOD1 protein levels in cerebrospinal fluid and serum. Tofersen downregulates cerebrospinal fluid neurofilament light chain, neurofilament heavy chain, amyloid-beta 1-40, amyloid-beta 1-42, neuropeptide Y, ubiquitin C-terminal hydrolase L1, neuropentraxins 1, 2, R, corticotropin-releasing hormone, IL-15, and serum neurofilament light chain, neurofilament heavy chain. Tofersen can be used for the research of superoxide dismutase 1-associated amyotrophic lateral sclerosis.

HY-13578S

Brivudine-¹³C,¹⁵N₂
Brivudine-¹³C, ¹⁵N₂ (Bromovinyldeoxyuridine-¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Brivudine. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.

HY-N7063S

Nerol-d₂
Nerol-d₂ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity.

HY-W012808S

2-Fluoro-1,3-bis(methyl)benzene-d₆
2-Fluoro-1,3-bis(methyl)benzene-d6 is the deuterium labeled 2-Fluoro-1,3-dimethylbenzene (HY-W012808).

HY-W585906S

3-O-Acetyltylosin-d₃
3-O-Acetyltylosin-d3 is a deuterated labeled 3-O-Acetyltylosin.

HY-W013068S

DMT-dT Phosphoramidite-¹³C₁₀,¹⁵N₂
DMT-dT Phosphoramidite-¹³C₁₀,¹⁵N₂ is the ¹³C and ¹⁵N labeled DMT-dT Phosphoramidite. DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

HY-W747639

Glycidyl Stearate-C_C3
Glycidyl Stearate-¹³C₃ is ¹³C labeled Glycidyl stearate. Oxiran-2-ylmethyl stearate is a compound belonging to the class of esters. It contains reactive oxirane or epoxy groups that give the molecule its unique properties. Oxiran-2-ylmethyl stearate is derived from stearic acid and epichlorohydrin, which are naturally occurring substances. Glycidyl stearate is commonly used in various industrial applications such as the production of coatings, adhesives and surfactants. It can also be used as a crosslinking agent in the manufacture of polymers and resins.

HY-B0661S

Tamsulosin-d₄
Tamsulosin-d₄ ((R)-(-)-YM12617 (free base)-d₄) is deuterium labeled Tamsulosin. Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α₁-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models.

HY-165696S

2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)-¹³C₂,¹⁵N₂
2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)-¹³C₂,¹⁵N₂ is ¹³C and ¹⁵N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium).

HY-165683S

Alternariol-3-beta-glucoside-d₃
Alternariol-3-beta-glucoside-d₃ (D-lysergic acid amide (LSA)) is deuterium labeled Alternariol-3-beta-glucoside.

HY-W714703S

Sodium 2-((2,6-dimethylphenyl)(2-(methoxy-d₃)ethyl)amino)-2-oxoethane-1-sulfonate
Sodium 2-((2,6-dimethylphenyl)(2-(methoxy-d₃)ethyl)amino)-2-oxoethane-1-sulfonate is deuterium labeled Sodium 2-((2,6-dimethylphenyl)(2-methoxyethyl)amino)-2-oxoethane-1-sulfonate.

HY-14854S

Tecarfarin-¹³C,d₃
Tecarfarin-¹³C,d₃ (ATI-5923-¹³C,d₃) is ¹³C labeled Tecarfarin. Tecarfarin is an orally active VKOR inhibitor with an IC₅₀ of 0.67 μM against VKORC1. Tecarfarin blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation.

HY-N0729S1

Linoleic acid-d₁₁
Linoleic acid-d₁₁ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism.

HY-135329S

(1R,3S-)Solifenacin-d₅ hydrochloride
(1R,3S-)Solifenacin-d₅ hydrochloride is the deuterium labeled Solifenacin hydrochloride. Solifenacin D₅ hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is a muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

HY-W777681

Triflusal-¹³C₆
Triflusal-13C6 is a C13-labeled Triflusal. Triflusal is a platelet aggregation inhibitor.

HY-B0723S2

Ospemifene-d₅
Ospemifene-d₅ (FC-1271a-d₅) is deuterium labeled Ospemifene. Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with K_is of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer.

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