Brivudine-13C,15N2
Brivudine-13C, 15N2 (Bromovinyldeoxyuridine-13C, 15N2) is 13C and 15N labeled Brivudine. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
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- Formule: C1013CH13Br15N2O5
- Masse moléculaire:336.11
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 69304-47-8
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Masse moléculaire 336.11
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Formule C1013CH13Br15N2O5
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SMILES
O=[13C]1[15N](C=C(C([15NH]1)=O)/C=C/Br)[C@@H]2O[C@@H]([C@H](C2)O)CO
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Synonyms
Bromovinyldeoxyuridine-13C,15N2; BVDU-13C,15N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Rabasseda X, et al. Brivudine: a herpes virostatic with rapid antiviral activity and once-daily dosing. Drugs Today (Barc). 2003 May;39(5):359-71. [Content Brief]
[3]. Keam SJ, et al. Brivudin (bromovinyl deoxyuridine). Drugs. 2004;64(18):2091-7; discussion 2098-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Brivudine-13C,15N2 Related Classifications
HY-13578S Related Classifications
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