Tamsulosin-d4
Tamsulosin-d4 ((R)-(-)-YM12617 (free base)-d4) is deuterium labeled Tamsulosin. Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models.
For research use only. We do not sell to patients.
- CAS No.: 1231943-97-7
- Formula: C20H24D4N2O5S
- Molecular Weight:412.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1231943-97-7
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Unlabeled Cas 106133-20-4
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Molecular Weight 412.54
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Formula C20H24D4N2O5S
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SMILES
NS(=O)(C1=C(C=CC(C[C@@H](C)NC([2H])([2H])C([2H])([2H])OC2=C(C=CC=C2)OCC)=C1)OC)=O
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Synonyms
(R)-(-)-YM12617 free base-d4; LY253351 free base-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Christopher Chapple, et al. Tamsulosin: an overview. World J Urol. 2002 Apr;19(6):397-404. [Content Brief]
[3]. William G. Montgomery, BA, et al. Tamsulosin Attenuates Abdominal Aortic Aneurysm Growth. Surgery. 2018 Nov; 164(5): 1087–1092. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)