1. Metabolic Enzyme/Protease
  2. Stearoyl-CoA Desaturase (SCD)

XEN723 

Cat. No.: HY-100249
Handling Instructions

XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.

For research use only. We do not sell to patients.

XEN723 Chemical Structure

XEN723 Chemical Structure

CAS No. : 1072803-08-7

Size Price Stock
1 mg USD 939 Get quote
5 mg USD 1502 Get quote
10 mg USD 2404 Get quote

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Related Small Molecules:

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  • References

Description

XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.

IC50 & Target

IC50: 45 nM (SCD1 in Mouse), 524 nM (SCD1 in HepG2 cell)[1]

In Vitro

XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively. XEN723 demonstrates an improvement in SCD1 in vitro potency of more than 560-fold compare to the original high throughput screen (HTS) hit[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3503 mL 11.7514 mL 23.5029 mL
5 mM 0.4701 mL 2.3503 mL 4.7006 mL
10 mM 0.2350 mL 1.1751 mL 2.3503 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

425.48

Formula

C₂₁H₂₀FN₅O₂S

CAS No.

1072803-08-7

SMILES

O=C(C1=C(C)N=C(N2CCN(CC3=CC=C(F)C=C3)C2=O)S1)NCC4=CC=CN=C4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
XEN723
Cat. No.:
HY-100249
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XEN723

Cat. No.: HY-100249