2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. AcBut

AcBut  (Synonyms: 4-(4-Acetyl-phenoxy)-butyric acid)

Cat. No.: HY-132261 Purity: 98.07%
COA
SDS
Handling Instructions Technical Support

AcBut (4-(4-Acetyl-phenoxy)-butyric acid) is a cleavable linker for Ozogamicin synthesis, and Ozogamicin is a drug-linker conjugate for ADC.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

AcBut

AcBut 화학구조

CAS No. : 65623-82-7

사이즈 가격 재고 수량
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

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AcBut Related Antibodies

Top Publications Citing Use of Products

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  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

AcBut (4-(4-Acetyl-phenoxy)-butyric acid) is a cleavable linker for Ozogamicin synthesis, and Ozogamicin is a drug-linker conjugate for ADC[1].

In Vitro

AcBut is a degradable linker for Ozogamicin that is used in the synthesis of Ozogamicin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AcBut Related Antibodies
분자량

222.24

화학식

C12H14O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCCOC1=CC=C(C(C)=O)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도
In Vitro: 

DMSO : 125 mg/mL (562.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4996 mL 22.4982 mL 44.9964 mL
5 mM 0.8999 mL 4.4996 mL 8.9993 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4996 mL 22.4982 mL 44.9964 mL 112.4910 mL
5 mM 0.8999 mL 4.4996 mL 8.9993 mL 22.4982 mL
10 mM 0.4500 mL 2.2498 mL 4.4996 mL 11.2491 mL
15 mM 0.3000 mL 1.4999 mL 2.9998 mL 7.4994 mL
20 mM 0.2250 mL 1.1249 mL 2.2498 mL 5.6245 mL
25 mM 0.1800 mL 0.8999 mL 1.7999 mL 4.4996 mL
30 mM 0.1500 mL 0.7499 mL 1.4999 mL 3.7497 mL
40 mM 0.1125 mL 0.5625 mL 1.1249 mL 2.8123 mL
50 mM 0.0900 mL 0.4500 mL 0.8999 mL 2.2498 mL
60 mM 0.0750 mL 0.3750 mL 0.7499 mL 1.8748 mL
80 mM 0.0562 mL 0.2812 mL 0.5625 mL 1.4061 mL
100 mM 0.0450 mL 0.2250 mL 0.4500 mL 1.1249 mL
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AcBut Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AcBut65623-82-74-(4-Acetyl-phenoxy)-butyric acidADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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상품명:
AcBut
Cat. No.:
HY-132261
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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