2. Metabolic Enzyme/Protease
  3. Aldose Reductase
  4. ALR2-IN-1

ALR2-IN-1 is a potent and selective ALR2 inhibitor (IC50=1.42 μM). ALR2-IN-1 shows antioxidant and antiglycative properties. ALR2-IN-1 can be used in diabetic complication research.

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ALR2-IN-1

ALR2-IN-1 화학구조

CAS No. : 2799695-54-6

사이즈 가격 재고 수량
무료 샘플 (0.1 - 0.2 mg)   지금 신청하기  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

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ALR2-IN-1 Related Antibodies

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제품 설명

ALR2-IN-1 is a potent and selective ALR2 inhibitor (IC50=1.42 μM). ALR2-IN-1 shows antioxidant and antiglycative properties. ALR2-IN-1 can be used in diabetic complication research[1].

IC50 & Target

IC50: 1.42 μM (ALR2) >100 μM (ALR1)[1]
분자량

315.39

화학식

C16H17N3O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=CC=C(O)C(/C=N/NC(NC2=CC=CC(OC)=C2)=S)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도
In Vitro: 

DMSO : 100 mg/mL (317.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1707 mL 15.8534 mL 31.7068 mL
5 mM 0.6341 mL 3.1707 mL 6.3414 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1707 mL 15.8534 mL 31.7068 mL 79.2669 mL
5 mM 0.6341 mL 3.1707 mL 6.3414 mL 15.8534 mL
10 mM 0.3171 mL 1.5853 mL 3.1707 mL 7.9267 mL
15 mM 0.2114 mL 1.0569 mL 2.1138 mL 5.2845 mL
20 mM 0.1585 mL 0.7927 mL 1.5853 mL 3.9633 mL
25 mM 0.1268 mL 0.6341 mL 1.2683 mL 3.1707 mL
30 mM 0.1057 mL 0.5284 mL 1.0569 mL 2.6422 mL
40 mM 0.0793 mL 0.3963 mL 0.7927 mL 1.9817 mL
50 mM 0.0634 mL 0.3171 mL 0.6341 mL 1.5853 mL
60 mM 0.0528 mL 0.2642 mL 0.5284 mL 1.3211 mL
80 mM 0.0396 mL 0.1982 mL 0.3963 mL 0.9908 mL
100 mM 0.0317 mL 0.1585 mL 0.3171 mL 0.7927 mL
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ALR2-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALR2-IN-12799695-54-6Aldose Reductaseantioxidantantiglycativediabetic complicationInhibitorinhibitorinhibit

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상품명:
ALR2-IN-1
Cat. No.:
HY-150630
수량:
MCE Japan Authorized Agent:

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