1. Immunology/Inflammation
  2. FLAP
  3. AM103 free acid

AM103 (free acid) is a selective FLAP inhibitor that can block the first step of the LT pathway, which is 5-LO activation. AM103 (free acid) can inhibit the production of LTB4 and cysteinyl leukotrienes (CysLT). AM103 (free acid) has anti-inflammatory activity in a mouse model of chronic lung inflammation and can extend the survival time of mice injected with platelet-activating factor. AM103 (free acid) can be used for research on respiratory diseases such as asthma.

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AM103 free acid

AM103 free acid 화학구조

CAS No. : 936349-47-2

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제품 설명

AM103 (free acid) is a selective FLAP inhibitor that can block the first step of the LT pathway, which is 5-LO activation. AM103 (free acid) can inhibit the production of LTB4 and cysteinyl leukotrienes (CysLT). AM103 (free acid) has anti-inflammatory activity in a mouse model of chronic lung inflammation and can extend the survival time of mice injected with platelet-activating factor. AM103 (free acid) can be used for research on respiratory diseases such as asthma[1].

분자량

609.78

화학식

C36H39N3O4S

CAS No.
SMILES

O=C(C(C)(CC1=C(C2=C(N1CC3=CC=C(C4=CC=C(OC)N=C4)C=C3)C=CC(OCC5=NC=CC=C5)=C2)SC(C)(C)C)C)O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
AM103 free acid
Cat. No.:
HY-14162
수량:
MCE Japan Authorized Agent: