Anti-Mouse F4/80 Antibody (CI:A3-1) 

Anti-Mouse F4/80 Antibody (CI:A3-1) is an anti-mouse F4/80 IgG2b monoclonal antibody. Anti-Mouse F4/80 Antibody (CI:A3-1) can clear macrophages. Anti-Mouse F4/80 Antibody (CI:A3-1) can be used for research on inflammation conditions such as endometriosis. Anti-Mouse F4/80 Antibody (CI:A3-1) often used for flow cytometry analysis and immunohistochemical analysis^[1][2].

Rat IgG2b kappa

Rat IgG2b kappa, Isotype Control

Mouse

F4/80

Anti-Mouse F4/80 Antibody (CI:A3-1) (0.80 μg/g/mice, i.p., once every 2 days, on day 0, 2, 4, 6, 8 and 10) can effectively clear macrophages in female Balb/C mice with an endometriosis model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

13733  [NCBI]

Q61549

in vivo Monocyte/Macrophage depletion; Functional assays; Immunohistochemistry (paraffin); Immuno

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

Liquid

Colorless to light yellow

[Anti-Mouse F4/80 Antibody (CI:A3-1)]

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Bacci M, et al. Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease. Am J Pathol. 2009 Aug;175(2):547-56.  [Content Brief]

  [2]. Steenbrugge J, et al. Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer. J Exp Clin Cancer Res. 2018 Aug 15;37(1):191.  [Content Brief]