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Results for "

gadd45

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bcl-2 Family (1) DNA/RNA Synthesis (3) JAK (2) JNK (1) MDM-2/p53 (3) Reference Standards (1) Small Interfering RNA (siRNA) (9)
By Research Areas:	Cancer (6)
Oligonucleotides:	Rat Pre-designed siRNA Sets (3) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (3) siRNAs (9)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100538

DTP3 1 Publications Verification	DNA/RNA Synthesis JAK	Cancer
DTP3 TFA is a potent and selective *GADD45β/MKK7* inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

HY-122578

P53R3	MDM-2/p53	Cancer
P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53 ^R175H, p53 ^R248W and p53 ^R273H. P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and p53 ^M237I to several target gene promoters. P53R3 strongly enhances the mRNA, total protein and cell surface expression of the death receptor death receptor 5 (DR5). P53R3 is used for cancer research .

HY-RS05229

GADD45A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GADD45A Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GADD45A Human Pre-designed siRNA Set A GADD45A Human Pre-designed siRNA Set A

HY-100538A

DTP3 TFA 1 Publications Verification	DNA/RNA Synthesis JNK	Cancer
DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

HY-179129

AKT-100	MDM-2/p53	Cancer
AKT-100 is a p53 reactivation agent. AKT-100 significantly inhibits the proliferation of various ovarian and endometrial cancer cells at low concentrations. AKT-100 can upregulate cell cycle regulatory genes (such as p21, GADD45) and pro apoptotic genes (such as NOXA, DR5), and inhibit DNA repair pathways. AKT-100 is commonly used in cancer research .

HY-RS17861

Gadd45a Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gadd45a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gadd45a Mouse Pre-designed siRNA Set A Gadd45a Mouse Pre-designed siRNA Set A

HY-126311

4-Hydroxyresveratrol 3,4,5,4'-Tetrahydroxystibene	MDM-2/p53 Bcl-2 Family Apoptosis	Cancer
4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA .

HY-RS05231

GADD45G Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GADD45G Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GADD45G Human Pre-designed siRNA Set A GADD45G Human Pre-designed siRNA Set A

HY-RS26335

Gadd45g Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gadd45g Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45g gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gadd45g Rat Pre-designed siRNA Set A Gadd45g Rat Pre-designed siRNA Set A

HY-RS05230

GADD45B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GADD45B Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GADD45B Human Pre-designed siRNA Set A GADD45B Human Pre-designed siRNA Set A

HY-RS18014

Gadd45b Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gadd45b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gadd45b Mouse Pre-designed siRNA Set A Gadd45b Mouse Pre-designed siRNA Set A

HY-RS24330

Gadd45a Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gadd45a Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gadd45a Rat Pre-designed siRNA Set A Gadd45a Rat Pre-designed siRNA Set A

HY-RS19838

Gadd45g Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gadd45g Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45g gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gadd45g Mouse Pre-designed siRNA Set A Gadd45g Mouse Pre-designed siRNA Set A

HY-RS24487

Gadd45b Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gadd45b Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gadd45b Rat Pre-designed siRNA Set A Gadd45b Rat Pre-designed siRNA Set A

HY-100538R

DTP3 (Standard)	DNA/RNA Synthesis Reference Standards JAK	Cancer
DTP3 (Standard) is the analytical standard of DTP3 (HY-100538). This product is intended for research and analytical applications. DTP3 TFA is a potent and selective GADD45β/MKK7 inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

Cat. No.	Product Name	Target	Research Area

HY-100538

DTP3 1 Publications Verification	DNA/RNA Synthesis JAK	Cancer
DTP3 TFA is a potent and selective *GADD45β/MKK7* inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

HY-100538A

DTP3 TFA 1 Publications Verification	DNA/RNA Synthesis JNK	Cancer
DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

HY-100538R

DTP3 (Standard)	DNA/RNA Synthesis Reference Standards JAK	Cancer
DTP3 (Standard) is the analytical standard of DTP3 (HY-100538). This product is intended for research and analytical applications. DTP3 TFA is a potent and selective GADD45β/MKK7 inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

Species:	Human (3)
Tag:	His (3)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70326

	GADD45A/DDIT-1 Protein, Human (His) rHuGrowth arrest and DNA damage-inducible protein gadd45 alpha/gadd45A, His; Growth Arrest and DNA Damage-Inducible Protein gadd45 Alpha; DNA Damage-Inducible Transcript 1 Protein; DDIT-1; gadd45A; DDIT1; gadd45	Human	E. coli
	GADD45A/DDIT-1 protein regulates p38 MAPK by inhibiting p88 phosphorylation in T cells, thereby affecting cell signaling pathways. It can regulate the PCNA-CDK complex, promote DNA excision repair, and hinder S phase entry. GADD45A/DDIT-1 Protein, Human (His) is the recombinant human-derived GADD45A/DDIT-1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70212

	GADD45B Protein, Human (His) rHuGrowth arrest and DNA damage-inducible protein gadd45 beta/gadd45B, His; Growth Arrest and DNA Damage-Inducible Protein gadd45 Beta; Myeloid Differentiation Primary Response Protein MyD118; Negative Growth Regulatory Protein MyD118; gadd45B; MYD118	Human	E. coli
	GADD45B Protein, a pivotal mediator, regulates growth and apoptosis by activating the MTK1/MEKK4 MAPKKK signaling pathway. Interacting with GADD45GIP1, it forms a complex that modulates cellular responses under stress. Its central role in growth and apoptosis underscores its significance in orchestrating cellular processes, positioning GADD45B as a key player in the intricate network of signaling pathways governing cell fate decisions. GADD45B Protein, Human (His) is the recombinant human-derived GADD45B protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70218

	GADD45G/DDIT2 Protein, Human (His) rHuGrowth arrest and DNA damage-inducible protein gadd45 gamma/gadd45G, His; Growth Arrest and DNA Damage-Inducible Protein gadd45 Gamma; Cytokine-Responsive Protein CR6; DNA Damage-Inducible Transcript 2 Protein; DDIT-2; gadd45G; CR6; DDIT2	Human	E. coli
	GADD45G/DDIT2 protein is a key mediator that regulates growth and apoptosis through the MTK1/MEKK4 MAPKKK signaling pathway. Concentration-dependent homodimerization enhances its growth inhibitory activity and interaction with PCNA, suggesting a role in DNA repair. GADD45G/DDIT2 Protein, Human (His) is the recombinant human-derived GADD45G/DDIT2 protein, expressed by E. coli , with N-6*His labeled tag.

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Host:	Mouse (5) Rabbit (1)
Reactivity:	Transfected (1) Human (5) Rat (5) Mouse (5)
Application:	IHC-P (2) ICC/IF (2) IP (2) WB (4)
Isotype:	IgG (1) IgG1 (4)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81331

	GADD45A Antibody (YA1076) DDIT1; gadd45	WB	Human, Mouse, Rat
	GADD45A Antibody (YA1076) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GADD45A.

HY-P81331A

	GADD45A Antibody (YA1076)(PBS only) DDIT1; gadd45	WB	Human, Mouse, Rat
	GADD45A Antibody (YA1076) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GADD45A.

HY-P85606

	GADD45A Antibod (YA5298) DDIT 1; DDIT-1; DDIT1; DNA damage inducible transcript 1; DNA damage-inducible transcript 1 protein; GA45A_HUMAN; gadd45; gadd45A; Growth arrest and DNA damage inducible 45 alpha; Growth arrest and DNA damage inducible alpha; Growth arrest and DNA damage-inducible protein gadd45 alpha.	WB	Transfected
	GADD45A Antibody (YA5298) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GADD45A.

HY-P88217

	GADD45G Antibody (YA7901) CR6; DDIT2; gadd45gamma; GRP17	IHC-P, ICC/IF, IP	Human, Mouse, Rat
	GADD45G Antibody (YA7901) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GADD45G.

HY-P88217A

	GADD45G Antibody (YA7901)(PBS only) CR6; DDIT2; gadd45gamma; GRP17	IHC-P, ICC/IF, IP	Human, Mouse, Rat
	GADD45G Antibody (YA7901) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GADD45G.

HY-P87221

	GADD45B Antibody (YA6909) GA45B_HUMAN antibody	WB	Human, Mouse, Rat
	GADD45B Antibody (YA6909) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GADD45B.