2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Axomadol

Axomadol (EN3324) is a centrally active analgesic agent with opioid agonistic properties and inhibitory effects on the reuptake of monoamines.

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Axomadol

Axomadol Estructura química

No. CAS : 187219-99-4

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Descripciòn

Axomadol (EN3324) is a centrally active analgesic agent with opioid agonistic properties and inhibitory effects on the reuptake of monoamines[1].

Ensayo clínico
Peso molecular

279.38

Fòrmula

C16H25NO3
No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@@]1(C2=CC=CC(OC)=C2)C[C@@H](O)CC[C@H]1CN(C)C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (357.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5794 mL 17.8968 mL 35.7935 mL
5 mM 0.7159 mL 3.5794 mL 7.1587 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5794 mL 17.8968 mL 35.7935 mL 89.4839 mL
5 mM 0.7159 mL 3.5794 mL 7.1587 mL 17.8968 mL
10 mM 0.3579 mL 1.7897 mL 3.5794 mL 8.9484 mL
15 mM 0.2386 mL 1.1931 mL 2.3862 mL 5.9656 mL
20 mM 0.1790 mL 0.8948 mL 1.7897 mL 4.4742 mL
25 mM 0.1432 mL 0.7159 mL 1.4317 mL 3.5794 mL
30 mM 0.1193 mL 0.5966 mL 1.1931 mL 2.9828 mL
40 mM 0.0895 mL 0.4474 mL 0.8948 mL 2.2371 mL
50 mM 0.0716 mL 0.3579 mL 0.7159 mL 1.7897 mL
60 mM 0.0597 mL 0.2983 mL 0.5966 mL 1.4914 mL
80 mM 0.0447 mL 0.2237 mL 0.4474 mL 1.1185 mL
100 mM 0.0358 mL 0.1790 mL 0.3579 mL 0.8948 mL
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Axomadol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Axomadol187219-99-4EN3324EN 3324EN-3324Opioid Receptoropioidanalgesicmonoaminesnoradrenalineserotonin5-hydroxytrypyamine5-HTInhibitorinhibitorinhibit

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Nombre del producto:
Axomadol
Cat. No.:
HY-U00031
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