Azido Myristic Acid

製品番号: HY-151855 純度: 99.89%: Data Sheet SDS COA 取扱説明書
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Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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Azido Myristic Acid 構造式

CAS 番号 : 80667-36-3

容量	価格（税別）	在庫状況	数量
5 mg	$38	在庫あり	Estimated Time of Arrival: December 31
10 mg	$60	在庫あり	Estimated Time of Arrival: December 31
25 mg	$95	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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生物活性
純度とドキュメンテーション
参考文献
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製品説明

Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique^[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cellular Effect

Cell Line	Type	Value	Description	References
Huh-7	CC₅₀	>50 μM Compound: 12-Azidododecanoic acid	Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo analysis Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo analysis	[PMID: 34583312]

体外実験

Azido Myristic Acid could be a suitable substrate for enzymes. Due to the very small size of the azide group and its complete absence in any natural molecules the presence of azide group does affect the biodistribution of azido palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

241.33

分子式

C₁₂H₂₃N₃O₂

CAS 番号

80667-36-3

Appearance

Solid-Liquid Mixture

Color

White to off-white

SMILES

[N-]=[N+]=NCCCCCCCCCCCC(O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

純度: 99.89%

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データシート (261 KB) SDS (795 KB)

COA (239 KB) HNMR (242 KB) RP-HPLC (234 KB) MS (72 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. [Content Brief]