2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Azidoacetic Acid

Azidoacetic Acid  (Synonyms: 2-Azidoacetic acid)

製品番号: HY-151719 純度: 99.09%
COA 取扱説明書 Technical Support

Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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Azidoacetic Acid

Azidoacetic Acid 構造式

CAS 番号 : 18523-48-3

容量 価格（税別） 在庫状況 数量
100 mg $50 在庫あり
250 mg $84 在庫あり
500 mg $110 在庫あり
1 g $140 在庫あり
5 g $269 在庫あり
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50 g   お問い合わせ  

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Azidoacetic Acid 関連抗体

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製品説明

Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

体外実験

Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension —Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Azidoacetic Acid 関連抗体
分子量

101.06

分子式

C2H3N3O2
CAS 番号
Appearance

Liquid (Density: 1.350 g/cm3)

Color

Colorless to light yellow

SMILES

[N-]=[N+]=NCC(O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 100 mg/mL (989.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.8951 mL 49.4756 mL 98.9511 mL
5 mM 1.9790 mL 9.8951 mL 19.7902 mL
10 mM 0.9895 mL 4.9476 mL 9.8951 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.09%

COA (242 KB) HNMR (228 KB) LCMS (88 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 9.8951 mL 49.4756 mL 98.9511 mL 247.3778 mL
5 mM 1.9790 mL 9.8951 mL 19.7902 mL 49.4756 mL
10 mM 0.9895 mL 4.9476 mL 9.8951 mL 24.7378 mL
15 mM 0.6597 mL 3.2984 mL 6.5967 mL 16.4919 mL
20 mM 0.4948 mL 2.4738 mL 4.9476 mL 12.3689 mL
25 mM 0.3958 mL 1.9790 mL 3.9580 mL 9.8951 mL
30 mM 0.3298 mL 1.6492 mL 3.2984 mL 8.2459 mL
40 mM 0.2474 mL 1.2369 mL 2.4738 mL 6.1844 mL
50 mM 0.1979 mL 0.9895 mL 1.9790 mL 4.9476 mL
60 mM 0.1649 mL 0.8246 mL 1.6492 mL 4.1230 mL
80 mM 0.1237 mL 0.6184 mL 1.2369 mL 3.0922 mL
100 mM 0.0990 mL 0.4948 mL 0.9895 mL 2.4738 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Azidoacetic Acid Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azidoacetic Acid18523-48-32-Azidoacetic acidADC LinkerAntibody-drug conjugates linkerazidePROTACsmall molecule toolInhibitorinhibitorinhibit

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