2. Inhibitorische Antikörper
  3. Biosimilar Antibodies
  4. Monoclonal Antibodies
  5. Bentracimab

Bentracimab  (Synonyms: PB 2452; MEDI 2452)

Art. -Nr.: HY-P99469 Reinheit: 99.0%
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Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor (HY-1006) and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor.

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CAS. Nr. : 2260568-31-6

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Bentracimab Related Antibodies

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Beschreibung

Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor (HY-1006) and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor[1].

Isotype

Fab-G1-lambda
Species Reactivity

Human
IC50 & Target

ticagrelor
In Vivo

Bentracimab‐bound Ticagrelor is primarily eliminated together with Bentracimab in the kidneys, and not recycled to the plasma[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Klinische Studie
Gene ID

64805  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Bentracimab]
Versand

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Fab-G1-lambda
Reinheit & Dokumentation
Verweise
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Bentracimab Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bentracimab2260568-31-6PB 2452 MEDI 2452PB2452PB-2452MEDI2452MEDI 2452MEDI-2452OthersTicagrelorantiplateletInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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