2. Anti-infection
  3. Bacterial
  4. Cecropin A (1-7)-Melittin A (2-9)

Cecropin A (1-7)-Melittin A (2-9)  (Synonyms: Oct-CA(1-7)M(2-9))

Cat. No.: HY-P3914 Pureté: 99.50%
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Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides.

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Synthèse de peptides personnalisée

Cecropin A (1-7)-Melittin A (2-9)

Cecropin A (1-7)-Melittin A (2-9) Chemical Structure

CAS No. : 157606-25-2

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Cecropin A (1-7)-Melittin A (2-9) Related Antibodies

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Description

Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides[1].

In Vitro

Cecropin A (1-7)-Melittin A (2-9) (0-64 mg/L, 48 h) inhibits E. coli ATCC 25922, Staphylococcus aureus ATCC 29213, B. fragilis NCTC 9343 and C. pefringens ATCC 13124 with the MIC values of 8 mg/L, 32 mg/L, 8 mg/L and 64 mg/L, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cecropin A (1-7)-Melittin A (2-9) Related Antibodies
Masse moléculaire

1770.30

Formule

C89H152N22O15
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

KWKLFKKIGAVLKVL-NH2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvant et solubilité
In Vitro: 

DMSO : 100 mg/mL (56.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (5.65 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5649 mL 2.8244 mL 5.6488 mL
5 mM 0.1130 mL 0.5649 mL 1.1298 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation
Références

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.5649 mL 2.8244 mL 5.6488 mL 14.1219 mL
5 mM 0.1130 mL 0.5649 mL 1.1298 mL 2.8244 mL
DMSO 10 mM 0.0565 mL 0.2824 mL 0.5649 mL 1.4122 mL
15 mM 0.0377 mL 0.1883 mL 0.3766 mL 0.9415 mL
20 mM 0.0282 mL 0.1412 mL 0.2824 mL 0.7061 mL
25 mM 0.0226 mL 0.1130 mL 0.2260 mL 0.5649 mL
30 mM 0.0188 mL 0.0941 mL 0.1883 mL 0.4707 mL
40 mM 0.0141 mL 0.0706 mL 0.1412 mL 0.3530 mL
50 mM 0.0113 mL 0.0565 mL 0.1130 mL 0.2824 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cecropin A (1-7)-Melittin A (2-9) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cecropin A (1-7)-Melittin A (2-9)157606-25-2Oct-CA(1-7)M(2-9)Bacterialantimicrobial peptideantimalarialGram-positive bacteriaGram-negative aerobic bacteriaInhibitorinhibitorinhibit

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