Oct-CA(1-7)M(2-9)

By Targets:	Oct3/4 (6) Adrenergic Receptor (3) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (3) Endogenous Metabolite (2) Fungal (1) Isotope-Labeled Compounds (4) Mitochondrial Metabolism (1) Reactive Oxygen Species (1) TET Protein (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Endocrinology (2) Infection (1) Metabolic Disease (4) Neurological Disease (2)

Targets Recommended: Oct3/4

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18773

Oct3/4-inducer-1
Oct3/4-inducer-1 (compound 2) is a potent *Oct3/4* inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4, and enhances its transcriptional activity in diverse human somatic cells .

HY-119672

Oct4 inducer-1	Oct3/4	Others
Oct4 inducer-1 (compound OAC-3) is a potent *Oct4* activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .

HY-W010410

Oct-1-en-3-ol	Others	Neurological Disease Metabolic Disease
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling .

HY-154951

Oct4 inducer-2	Oct3/4	Others
Oct4 inducer-2 is an *OCT4* inducer, which can maintain the formation of hiPSCs by promoting the expression of endogenous OCT4, which can be used in anti-aging research .

HY-W010410S

Oct-1-en-3-ol-d3	Others Isotope-Labeled Compounds	Metabolic Disease
Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-113146

2-Octenal Oct-2-enal	Biochemical Assay Reagents	Others
2-Octenal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3914

Cecropin A (1-7)-Melittin A (2-9) Oct-CA(1-7)M(2-9)	Bacterial	Infection
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .

HY-W046906

(E)-Oct-2-enoic acid

Endogenous Metabolite Metabolic Disease

(E)-Oct-2-enoic acid is an endogenous metabolite.

*(E)-Oct-2-enoic acid*	Endogenous Metabolite	Metabolic Disease
(E)-Oct-2-enoic acid is an endogenous metabolite.

HY-W046907

*Ethyl (E)-oct-2-enoate* trans-2-Octenoic acid ethyl ester	Biochemical Assay Reagents	Others
Ethyl (E)-oct-2-enoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W134163S

(E)-Oct-2-enal-d2

trans-2-Octen-1-al-d₂
Isotope-Labeled Compounds Others

(E)-Oct-2-enal-d₂ is deuterated labeled 1-Octen-3-one.
HY-12884

OAC2

Oct3/4 Others

OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.

*(E)-Oct-2-enal-d2* trans-2-Octen-1-al-d₂	Isotope-Labeled Compounds	Others
(E)-Oct-2-enal-d₂ is deuterated labeled 1-Octen-3-one.

OAC2	Oct3/4	Others
OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.

HY-N7063S1

Nerol-d6	Mitochondrial Metabolism Fungal Endogenous Metabolite Reactive Oxygen Species Isotope-Labeled Compounds
Nerol-d₆ is deuterated labeled Oct-1-en-3-ol (HY-W010410). Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling .

HY-18771

O4I1

Oct3/4 Others

O4I1 is as a potent Oct3/4 inducer.

O4I1	Oct3/4	Others
O4I1 is as a potent Oct3/4 inducer.

HY-N0750

Monocrotaline Maximum Cited Publications 15 Publications Verification Crotaline	Others	Metabolic Disease Cancer
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits *OCT-1* and *OCT-2* with IC₅₀s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. ^[2][6][8].

HY-12303

OAC1 1 Publications Verification	Oct3/4 TET Protein	Cancer
OAC1 is a potent *Oct4* activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and TET1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .

HY-W106629

3-Octenoic acid	Biochemical Assay Reagents	Others
Oct-3-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B0193A

Prazosin hydrochloride 5+ Cited Publications	Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders . Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC₅₀ of 0.15 nM .Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC₅₀s of 1.8, and 13 μM, respectively .

HY-B0193AR

Prazosin hydrochloride (Standard)	Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Prazosin (hydrochloride) (Standard) is the analytical standard of Prazosin (hydrochloride). This product is intended for research and analytical applications. Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders . Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC₅₀ of 0.15 nM .Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC₅₀s of 1.8, and 13 μM, respectively .

HY-18772

O4I2

Oct3/4 Others

O4I2 is a potent Oct3/4 inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1 .

O4I2	Oct3/4	Others
O4I2 is a potent *Oct3/4* inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1 .

HY-155528

O4I4	Others	Others
O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research .

HY-W142921S

Allyl methyl disulfide-d3

methyl prop-2-en-1-yl disulfide-d₃
Isotope-Labeled Compounds Others

Allyl methyl disulfide-d₃ is deuterated labeled (E)-Oct-2-enal.

Allyl methyl disulfide-d3 methyl prop-2-en-1-yl disulfide-d₃	Isotope-Labeled Compounds	Others
Allyl methyl disulfide-d₃ is deuterated labeled (E)-Oct-2-enal.

HY-N2003

D-Tetrahydropalmatine
D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis . D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors . D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor .

HY-103216A

RWJ52353 hydrochloride	Adrenergic Receptor	Neurological Disease
RWJ-52353 hydrochloride is an orally potent, highly selective α2D adrenergic receptor agonist (Ki: 1.5 nM) with potential analgesic effects. RWJ-52353 hydrochloride demonstrated analgesic activity in abdominal tests in rats and mice, and improved agitation in mice in the hot plate test and tail flick test. RWJ-52353 hydrochloride also regulates the organic cation transporter (OCT) subtype, inhibiting rOCT1 and rOCT2 with IC₅₀s of 100 μM and 20 μM respectively; it also activates rOCT3, affecting [3H]-1- in cells. Methyl-4-phenylpyridinium ([3H]MPP) transport .

Cat. No.	Product Name

HY-L039

Reprogramming Compound Library	2048 compounds
Techniques for reprogramming somatic cells create new opportunities for drug screening, disease modeling, artificial organ development, and cell therapy. The development of reprogramming techniques has grown exponentially since Yamanaka reprogrammed somatic cells to become induced pluripotent stem cells (iPSCs) using four transcription factors, OCT4, SOX2, KLF4, and c-MYC in 2006. Despite the development of efficient reprogramming methods, most methods are inappropriate for clinical applications because they carry the risk of integrating exogenous genetic factors or use oncogenes. Alternative approaches, such as those based on miRNA, non-viral genes, non-integrative vectors, and small molecules, have been studied as possible solutions to the problems. Among these alternatives, small molecules are attractive options for clinical applications. Reprogramming using small molecules is inexpensive and easy to control in a concentration- and time-dependent manner. It offers a high level of cell permeability, ease of synthesis and standardization, and it is appropriate for mass-producing cells. MCE Reprogramming Compound Library contains a unique collection of 2048 compounds that act on reprogramming signaling pathways. These compounds are potential stimulators for reprogramming. This library is a useful tool for researching reprogramming and regenerative medicine.

Reprogramming Compound Library

2048 compounds

Techniques for reprogramming somatic cells create new opportunities for drug screening, disease modeling, artificial organ development, and cell therapy. The development of reprogramming techniques has grown exponentially since Yamanaka reprogrammed somatic cells to become induced pluripotent stem cells (iPSCs) using four transcription factors, OCT4, SOX2, KLF4, and c-MYC in 2006. Despite the development of efficient reprogramming methods, most methods are inappropriate for clinical applications because they carry the risk of integrating exogenous genetic factors or use oncogenes. Alternative approaches, such as those based on miRNA, non-viral genes, non-integrative vectors, and small molecules, have been studied as possible solutions to the problems. Among these alternatives, small molecules are attractive options for clinical applications. Reprogramming using small molecules is inexpensive and easy to control in a concentration- and time-dependent manner. It offers a high level of cell permeability, ease of synthesis and standardization, and it is appropriate for mass-producing cells.

MCE Reprogramming Compound Library contains a unique collection of 2048 compounds that act on reprogramming signaling pathways. These compounds are potential stimulators for reprogramming. This library is a useful tool for researching reprogramming and regenerative medicine.

Cat. No.	Product Name	Type

HY-113146

2-Octenal

Oct-2-enal
Biochemical Assay Reagents

2-Octenal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

2-Octenal Oct-2-enal	Biochemical Assay Reagents
2-Octenal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W046907

*Ethyl (E)-oct-2-enoate* trans-2-Octenoic acid ethyl ester	Biochemical Assay Reagents
Ethyl (E)-oct-2-enoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W106629

3-Octenoic acid

Biochemical Assay Reagents

Oct-3-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

3-Octenoic acid	Biochemical Assay Reagents
Oct-3-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P3914

Cecropin A (1-7)-Melittin A (2-9) Oct-CA(1-7)M(2-9)	Bacterial	Infection
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010410

Oct-1-en-3-ol	Microorganisms Source classification Plants	Others
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling .

HY-W046906

*(E)-Oct-2-enoic acid*	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(E)-Oct-2-enoic acid is an endogenous metabolite.

HY-N0750

Monocrotaline 10+ Cited Publications Crotaline	Structural Classification Alkaloids Pyrrole Alkaloids Classification of Application Fields Leguminosae Plants Crotalaria pallida Ait. Disease Research Fields Cancer	Others
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits *OCT-1* and *OCT-2* with IC₅₀s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. ^[2][6][8].

Species:	Human (2) Mouse (1)
Tag:	His (3) SUMO (1)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P78020

	Endoglycan/PODXL2 Protein, Human (HEK293, His) Endoglycan; PODLX2; brain-1; BRN1; EG; Oct-8; OTF8; UNQ1861/PRO3742	Human	HEK293
	Endoglycan/PODXL2 Protein, acting as a ligand for vascular selectins, enables the rapid rolling of leukocytes over vascular surfaces by engaging in high-affinity divalent cation-dependent interactions with E-, P-, and L-selectins. Through disulfide linkages, the protein forms homodimers and interacts with specific selectin proteins, including SELL, SELE, and SELP. These interactions highlight its pivotal role in mediating adhesive events crucial for leukocyte recruitment and vascular homeostasis. Endoglycan/PODXL2 Protein, Human (HEK293, His) is the recombinant human-derived Endoglycan/PODXL2 protein, expressed by HEK293, with C-His labeled tag. The total length of Endoglycan/PODXL2 Protein, Human (HEK293, His) is 468 a.a., with molecular weight of 70-115 kDa.

HY-P78021

	Endoglycan/PODXL2 Protein, Mouse (HEK293, His) Endoglycan; PODLX2; brain-1; BRN1; EG; Oct-8; OTF8; UNQ1861/PRO3742	Mouse	HEK293
	Endoglycan/PODXL2 Protein serves as a ligand for vascular selectins, enabling leukocyte rolling on vascular surfaces via high affinity interactions with E-, P-, and L-selectins. It exists as a disulfide-linked homodimer. Furthermore, Endoglycan/PODXL2 Protein interacts with SELL, SELE, and SELP, enhancing its role in leukocyte adhesion and trafficking in the vasculature. Endoglycan/PODXL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Endoglycan/PODXL2 protein, expressed by HEK293, with C-His labeled tag. The total length of Endoglycan/PODXL2 Protein, Mouse (HEK293, His) is 471 a.a., with molecular weight of 80-110 kDa.

HY-P72201

	GAPDH Protein, Human (His-SUMO) G3P_HUMAN; G3PD; G3PDH; GAPD; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; glyceraldehyde 3-PDH; Glyceraldehyde-3-phosphate dehydrogenase; HEL-S-162eP; KNC-NDS6; MGC102544; OCAS; p38 component; Oct1 coactivator in S phase; 38-KD component; peptidyl cysteine S nitrosylase GAPDH	Human	E. coli
	GAPDH, a multifunctional protein, acts as a key enzyme in glycolysis, catalyzing the conversion of G3P. It also functions as a nitrosylase, impacting nuclear processes. In addition, it influences cytoskeleton organization, associates with CHP1, participates in transcript-selective translation inhibition, contributes to immune responses, and mediates nuclear events through S-nitrosylation of target proteins. GAPDH Protein, Human (His-SUMO) is the recombinant human-derived GAPDH protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of GAPDH Protein, Human (His-SUMO) is 334 a.a., with molecular weight of ~51.9 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-W010410S

Oct-1-en-3-ol-d3
Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

Oct-1-en-3-ol-d3

Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-W134163S

(E)-Oct-2-enal-d2

(E)-Oct-2-enal-d₂ is deuterated labeled 1-Octen-3-one.

*(E)-Oct-2-enal-d2*
(E)-Oct-2-enal-d₂ is deuterated labeled 1-Octen-3-one.

HY-N7063S1

Nerol-d6
Nerol-d₆ is deuterated labeled Oct-1-en-3-ol (HY-W010410). Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling .

HY-W142921S

Allyl methyl disulfide-d3

Allyl methyl disulfide-d₃ is deuterated labeled (E)-Oct-2-enal.

Allyl methyl disulfide-d3
Allyl methyl disulfide-d₃ is deuterated labeled (E)-Oct-2-enal.

Cat. No.	Product Name	Application	Reactivity

HY-P80440

Oct-4 Antibody (YA837) MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; Oct3; Oct4; Octamer binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3; OTF 3; OTF 4; OTF	WB, ICC	Human, Mouse
Oct-4 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 39 kDa, targeting to POU5F1. It can be used for WB,ICC assays with tag free, in the background of Human, Mouse.

HY-P80770

Oct-4 Antibody MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; Oct3; Oct4; Octamer binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3; OTF 3; OTF 4; OTF	WB, IHC-P, ICC/IF, IP, ChIP	Human, Mouse
Oct-4 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to POU5F1. It can be used for WB,IHC-P,ICC/IF,IP,ChIP assays with tag free, in the background of Human, Mouse.

HY-P82681

SLC22A1 Antibody (YA2426)

hOct1; Oct1; Slc22a1
WB, FC Human

HY-P81782

45567 Antibody (YA1527) POU2F2; Oct2; OTF2; POU domain; class 2; transcription factor 2; Lymphoid-restricted immunoglobulin Octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2	WB, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P82467

BOB1 Antibody (YA2212)

BOB 1; BOB-1; OBF 1; OBF1; OCA B; OCA-B; OCAB; Oct binding factor 1; Pou2af1
WB, IHC-P, ICC/IF, FC Human
HY-P83085

SLC22A3 Antibody (YA2830)

SLC22A3; EMTH; Oct3; Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3
WB, IHC-P, FC Human

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