Cereulide-¹³C₆

Cat. No.: HY-P3003S Purity: 97%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Cereulide-¹³C₆ is a deuterated form of Cereulide. Cereulide is an orally active, blood-brain barrier-permeable emetic toxin. Cereulide acts as a potassium ionophore that inserts into membranes, forms complexes with K⁺, and transports K⁺ from the cytoplasm into the mitochondrial matrix. Cereulide disrupts the electrochemical gradient of the inner mitochondrial membrane, leading to mitochondrial swelling and dysfunction, uncoupling of oxidative phosphorylation, inhibition of ATP synthesis, ROS accumulation, and ultimately triggering apoptosis and autophagy. Cereulide exhibits multi-organ toxicity and can be used for research on emetic food poisoning.

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Cereulide-¹³C₆ 화학구조

CAS No. : 1487375-69-8

사이즈	가격	재고	수량
Solvent
20 μg (17.25 μM * 1 mL in Acetonitrile)		해외재고보유	Estimated Time of Arrival: December 31

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of Cereulide-¹³C₆:

Cereulide In-stock

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Biological Activity
순도&문서
References
고객리뷰

제품 설명	Cereulide-¹³C₆ is a deuterated form of Cereulide. Cereulide is an orally active, blood-brain barrier-permeable emetic toxin. Cereulide acts as a potassium ionophore that inserts into membranes, forms complexes with K⁺, and transports K⁺ from the cytoplasm into the mitochondrial matrix. Cereulide disrupts the electrochemical gradient of the inner mitochondrial membrane, leading to mitochondrial swelling and dysfunction, uncoupling of oxidative phosphorylation, inhibition of ATP synthesis, ROS accumulation, and ultimately triggering apoptosis and autophagy. Cereulide exhibits multi-organ toxicity and can be used for research on emetic food poisoning.
Application	1. This compound can be used as a tracer. 2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
분자량	1159.36
화학식	C₅₁¹³C₆H₉₆N₆O₁₈
CAS No.	1487375-69-8
Unlabeled CAS	157232-64-9
Appearance	Liquid
Color	Colorless to light yellow
SMILES	CC(C)C[C@H]1O[13C]([C@@H](NC([C@@H](OC([C@H](NC([C@H](O[13C]([C@@H](NC([C@@H](OC([C@H](NC([C@H](O[13C]([C@@H](NC([C@@H](OC([C@H](NC1=O)[13CH3])=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O)[13CH3])=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O)[13CH3])=O)C(C)C)=O)C(C)C)=O
선적	Room temperature in continental US; may vary elsewhere.
보관	Solution, -20°C, 2 years
순도&문서	Purity: 97.0% Select Batch: Data Sheet (276 KB) SDS (396 KB) COA (261 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et, al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]