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Results for "

columbianetin-

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

6

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0363
    (+)-Columbianetin
    2 Publications Verification

    (S)-columbianetin

    		 ERK JNK TGF-beta/Smad Others
    (+)-Columbianetin acts as an inhibitor of JNK and ERK as well as an activator of TGFβ signaling. (+)-Columbianetin inhibits UVA-induced phosphorylation of JNK and ERK, reduces the production of MMP-1, reverses UVA-induced collagen degradation, and alleviates UVA-mediated inhibition of Smad2/3 phosphorylation and translocation. (+)-Columbianetin regulates the AP-1 and ASK1-MAPK signaling pathways, inhibits the production of ROS, blocks sub-G1 cell cycle arrest, modulates the expression of MMP, and protects human keratinocytes against UVB-induced damage. (+)-Columbianetin is applicable to research related to skin aging .
    (+)-Columbianetin
  • HY-N0363A
    (+)-Columbianetin acetate
    2 Publications Verification

    (S)-columbianetin acetate

    		 Fungal Infection Inflammation/Immunology
    (S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .
    (+)-Columbianetin acetate
  • HY-N0363R
    (+)-Columbianetin (Standard)

    (S)-columbianetin (Standard)

    		 Reference Standards Fungal Infection Inflammation/Immunology
    (+)-Columbianetin (Standard) is the analytical standard of (+)-Columbianetin. This product is intended for research and analytical applications. (+)-Columbianetin is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .
    (+)-Columbianetin (Standard)
  • HY-N0363AR
    (+)-Columbianetin acetate (Standard)

    (S)-columbianetin acetate (Standard)

    		 Reference Standards Fungal Infection Inflammation/Immunology
    (+)-Columbianetin acetate (Standard) is the analytical standard of (+)-Columbianetin acetate. This product is intended for research and analytical applications. (S)-Columbianetin acetate is an isomer of Columbianetin. Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity .
    (+)-Columbianetin acetate (Standard)
  • HY-N12067
    Columbianetin β-D-glucopyranoside

    		Others Inflammation/Immunology
    Columbianetin β-D-glucopyranoside can be isolated from Angelicae pubescentis radix and has antiplatelet aggregation, anti-inflammatory and analgesic activities. Columbianetin β-D-glucopyranoside exerts significant protective effects against glutamate-induced toxicity .
    Columbianetin β-D-glucopyranoside
  • HY-N12968
    R-(-)-Columbianetin

    		Others Others
    R-(-)-Columbianetin is a known coumarin isolated from the root and stem bark of Skimmia reevesiana collected in Taiwan, with specific chemical structure and biological activity .
    R-(-)-Columbianetin

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