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  4. Copper Fluor-4

Copper Fluor-4  (Synonyms: CF4)

製品番号: HY-150086 純度: 95.11%
COA 取扱説明書 Technical Support

Copper Fluor-4 (CF4) is a Cu+-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity with a Kd value of 2.9×10−13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission).

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Copper Fluor-4

Copper Fluor-4 構造式

CAS 番号 : 2365532-64-3

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 824 在庫あり
Solution
10 mM * 1 mL in DMSO USD 824 在庫あり
Solid
1 mg $200 在庫あり
5 mg $500 在庫あり
10 mg $800 在庫あり
25 mg $1600 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 3 publication(s) in Google Scholar

Other Forms of Copper Fluor-4:

Copper Fluor-4 関連抗体

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製品説明

Copper Fluor-4 (CF4) is a Cu+-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity with a Kd value of 2.9×10−13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission)[1][2][3].

体外実験

Copper Fluor-4 (0.8 μM, 10 min) demonstrates localization of the copper in the soma region, which includes its localization in the perinuclear Golgi region in the PC-12-derived neurons[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Copper Fluor-4 関連抗体
体内実験

Copper Fluor-4 (2 µM, 24 h) can be used to assess changes in labile copper distributions in small living organisms such as zebrafish embryos[1].
Copper Fluor-4 (10 µM, 3 h) can be used to assess labile Cu levels with a Kd value of 2.9×10−13 M for a 1:1 copper:probe stoichiometry that is well-matched to monitor labile Cu pools by reversible Cu binding without depleting the total Cu store in worms[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

749.05

分子式

C38H47F3N2O2S4
CAS 番号
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=C1C=CC2=C(C3=C(C(F)(F)F)C=C(CN(CCSCCSCC)CCSCCSCC)C=C3)C4=C(C=C(N5CCCCC5)C=C4)OC2=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外: 

DMSO : 125 mg/mL (166.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3350 mL 6.6751 mL 13.3502 mL
5 mM 0.2670 mL 1.3350 mL 2.6700 mL
10 mM 0.1335 mL 0.6675 mL 1.3350 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

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体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.44%

COA (250 KB) HNMR (284 KB) LCMS (95 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3350 mL 6.6751 mL 13.3502 mL 33.3756 mL
5 mM 0.2670 mL 1.3350 mL 2.6700 mL 6.6751 mL
10 mM 0.1335 mL 0.6675 mL 1.3350 mL 3.3376 mL
15 mM 0.0890 mL 0.4450 mL 0.8900 mL 2.2250 mL
20 mM 0.0668 mL 0.3338 mL 0.6675 mL 1.6688 mL
25 mM 0.0534 mL 0.2670 mL 0.5340 mL 1.3350 mL
30 mM 0.0445 mL 0.2225 mL 0.4450 mL 1.1125 mL
40 mM 0.0334 mL 0.1669 mL 0.3338 mL 0.8344 mL
50 mM 0.0267 mL 0.1335 mL 0.2670 mL 0.6675 mL
60 mM 0.0223 mL 0.1113 mL 0.2225 mL 0.5563 mL
80 mM 0.0167 mL 0.0834 mL 0.1669 mL 0.4172 mL
100 mM 0.0134 mL 0.0668 mL 0.1335 mL 0.3338 mL
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Copper Fluor-4 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Copper Fluor-42365532-64-3CF4Copper Fluor4Copper Fluor 4CF 4CF-4Fluorescent DyeCopperCu+ probeInhibitorinhibitorinhibit

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製品名:
Copper Fluor-4
製品番号:
HY-150086
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