D-Leu-Pro-Arg-Rh110-D-Pro TFA

Art. -Nr.: HY-P6023A Reinheit: 99.20%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

D-Leu-Pro-Arg-Rh110-D-Pro TFA is a substrate for Factor Xa I (FXIa) with binding affinity. D-Leu-Pro-Arg-Rh110-D-Pro TFA consists of Rhodamine 110 (HY-D0817) linked to a peptide chain through a cleavable bond. Cleavable bond cleavage enhances fluorophore intensity. D-Leu-Pro-Arg-Rh110-D-Pro TFA can be used to detect FXIa activity.

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Kundenspezifische Peptidsynthese

D-Leu-Pro-Arg-Rh110-D-Pro TFA Chemische Struktur

Größe	Verfügbarkeit	Menge
1 mg	Auf Lager	Estimated Time of Arrival: December 31
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
25 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Auf Lager	Estimated Time of Arrival: December 31
100 mg	Angebot einholen
200 mg	Angebot einholen

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This product is a controlled substance and not for sale in your territory.

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Other Forms of D-Leu-Pro-Arg-Rh110-D-Pro TFA:

D-Leu-Pro-Arg-Rh110-D-Pro Angebot einholen
D-Leu-Pro-Arg-Rh110-D-Pro acetate Angebot einholen

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung

Molekulargewicht

793.91 (free base)

Formel

C₄₂H₅₁N₉O₇.xC₂HF₃O₂

Appearance

Solid

Color

Off-white to light yellow

Sequence

{d-Leu}-Pro-Arg-{Rh110}-{d-Pro}

Sequence Shortening

{d-Leu}-PR-{Rh110}-{d-Pro}

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

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Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.20%

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Data Sheet (273 KB) SDS (252 KB)

COA (256 KB) HNMR (262 KB) RP-HPLC (195 KB) LCMS (141 KB) Elemental Analysis Report (115 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63(15):8088-8113. [Content Brief]