2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Denagliptin

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings.

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Denagliptin

Denagliptin 화학구조

CAS No. : 483369-58-0

사이즈 가격 재고 수량
1 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
50 mg   견적 받기  
100 mg   견적 받기  
Synthetic products have potential research and development risk.

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Denagliptin Related Antibodies

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제품 설명

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings[1].

분자량

373.37

화학식

C20H18F3N3O
CAS No.
SMILES

O=C(N1[C@@H](C[C@@H](C1)F)C#N)[C@@H](N)C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Denagliptin Related Classifications

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  • 농도 희석 계산기

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Denagliptin483369-58-0GSK823093GSK 823093GSK-823093Endogenous MetaboliteInhibitorinhibitorinhibit

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Denagliptin
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