2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Denagliptin

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings.

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Denagliptin

Denagliptin Chemical Structure

CAS No. : 483369-58-0

Size Prix Stock Quantité
1 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
50 mg   Obtenir un devis  
100 mg   Obtenir un devis  
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Other Forms of Denagliptin:

Denagliptin Related Antibodies

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Description

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings[1].

Masse moléculaire

373.37

Formule

C20H18F3N3O
CAS No.
SMILES

O=C(N1[C@@H](C[C@@H](C1)F)C#N)[C@@H](N)C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Denagliptin Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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Keywords:

Denagliptin483369-58-0GSK823093GSK 823093GSK-823093Endogenous MetaboliteInhibitorinhibitorinhibit

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