1. Anti-infection
  2. Fungal
  3. Eberconazole

Eberconazole is a dichlorinated imidazole derivative with antifungal activity. Eberconazole is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole has potential for the study of dermatophytosis.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Eberconazole nitrate) usually boasts enhanced water solubility and stability.

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Eberconazole

Eberconazole Estructura química

No. CAS : 128326-82-9

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Descripciòn

Eberconazole is a dichlorinated imidazole derivative with antifungal activity. Eberconazole is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole has potential for the study of dermatophytosis[1][2].

In Vitro

Eberconazole (0.03-2 μg/mL, 7 days) exhibits significant antifungal activity against 200 strains of dermatophytes, with the strongest activity against Trichophyton rubrum and Trichophyton mentagrophytes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Experimentally induced cutaneous candidiasis guinea pig model[2]
Dosage: 1%-1.3% Eberconazole cream, approximately 1-1.3 g per animal
Administration: Topical application, twice daily, for 6 days
Result: Caused 90% of guinea pigs clinically recovered and lesions disappeared.
Peso molecular

329.22

Fòrmula

C18H14Cl2N2

No. CAS
SMILES

ClC1=CC(CCC2=C(C3N4C=NC=C4)C=CC=C2)=C3C(Cl)=C1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Eberconazole Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Eberconazole
Cat. No.:
HY-106542
Cantidad:
MCE Japan Authorized Agent: