ER Tracker Yellow  (Synonyms: BDNCA-346)

ER Tracker Yellow is an endoplasmic reticulum-targeted temperature-visible fluorescent probe. ER Tracker Yellow has high temperature sensitivity (3.9%/°C) and is not affected by pH and Ca²⁺ interference. ER Tracker Yellow can be used for real-time monitoring of local temperature changes in the ER area. ER Tracker Yellow maintains its function in fixed cells. ER Tracker Yellow is suitable for various cell lines and primary cells, such as HeLa cells, MEF cells, and other cells^[1][2].

575.72

C₂₇H₂₀BClF₅N₃O₃

1445108-32-6

Solid

Brown to black

O=C(CCl)NC1=CC=C(C2=C3C(C)=CC(/C=C/C4=CC(OC(F)(F)F)=CC=C4O)=[N]3[B+3]([F-])([F-])[N-]5C=CC=C25)C=C1

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

• [1]. Arai S, et al.A molecular fluorescent probe for targeted visualization of temperature at the endoplasmic reticulum. Sci Rep. 2014 Oct 21;4:6701.

  [2]. Dukic B, et al. Mild Hyperthermia-Induced Thermogenesis in the Endoplasmic Reticulum Defines Stress Response Mechanisms. Cells. 2024 Jul 3;13(13):1141.  [Content Brief]