1445108-32-6
Chemical Structure
ER Tracker Yellow
Synonym(s): BDNCA-346
- CAS No.: 1445108-32-6
- Formula:C27H20BClF5N3O3
- Molecular Weight:575.72
IUPAC Name: (4aS,6R)-6-amino-N-((S)-1-(4-chlorophenyl)-3-hydroxypropyl)-4,4a,5,6,7,8-hexahydro-9H-3-oxa-1,8a,9,11-tetraazadibenzo[cd,f]azulene-6-carboxamide
InChIKey: KELQILVKLNLBAG-RMKNXTFCSA-N
SMILES: O=C(CCl)NC1=CC=C(C2=C3C(C)=CC(/C=C/C4=CC(OC(F)(F)F)=CC=C4O)=[N]3[B+3]([F-])([F-])[N-]5C=CC=C25)C=C1
Biological Activity: ER Tracker Yellow is an endoplasmic reticulum-targeted temperature-visible fluorescent probe. ER Tracker Yellow has high temperature sensitivity (3.9%/°C) and is not affected by pH and Ca2+ interference. ER Tracker Yellow can be used for real-time monitoring of local temperature changes in the ER area. ER Tracker Yellow maintains its function in fixed cells. ER Tracker Yellow is suitable for various cell lines and primary cells, such as HeLa cells, MEF cells, and other cells[1][2].
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ER Tracker Yellow | 96.91% | ER Tracker Yellow is an endoplasmic reticulum-targeted temperature-visible fluorescent probe. ER Tracker Yellow has high temperature sensitivity (3.9%/°C) and is not affected by pH and Ca2+ interference. ER Tracker Yellow can be used for real-time monitoring of local temperature changes in the ER area. ER Tracker Yellow maintains its function in fixed cells. ER Tracker Yellow is suitable for various cell lines and primary cells, such as HeLa cells, MEF cells, and other cells. | ||||||||||||||||||||
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- [1]. Arai S, et al.A molecular fluorescent probe for targeted visualization of temperature at the endoplasmic reticulum. Sci Rep. 2014 Oct 21;4:6701.
- [2]. Dukic B, et al. Mild Hyperthermia-Induced Thermogenesis in the Endoplasmic Reticulum Defines Stress Response Mechanisms. Cells. 2024 Jul 3;13(13):1141. [Content Brief]
Keywords
