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  2. Environmental Pollutants Herbicide
  3. Florasulam

Florasulam is a targeted post-emergent herbicide belonging to the triazolopyrimidine sulfonanilide class, which functions by inhibiting acetolactate synthase (ALS) in plants. Located in the chloroplasts, ALS plays a crucial role in the biosynthesis of branched-chain amino acids. When Florasulam inhibits ALS, it disrupts plant cell division, reduces growth, and ultimately leads to plant death.

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Florasulam

Florasulam Estructura química

No. CAS : 145701-23-1

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
250 mg En stock
500 mg En stock
1 g En stock
5 g En stock
10 g En stock
50 g   Obtener un presupuesto  

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Other Forms of Florasulam:

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Descripciòn

Florasulam is a targeted post-emergent herbicide belonging to the triazolopyrimidine sulfonanilide class, which functions by inhibiting acetolactate synthase (ALS) in plants. Located in the chloroplasts, ALS plays a crucial role in the biosynthesis of branched-chain amino acids. When Florasulam inhibits ALS, it disrupts plant cell division, reduces growth, and ultimately leads to plant death.

Peso molecular

359.28

Fòrmula

C12H8F3N5O3S

No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=S(NC1=C(F)C=CC=C1F)(C2=NN3C(OC)=NC=C(F)C3=N2)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvente y solubilidad
In Vitro: 

DMSO : 50 mg/mL (139.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7833 mL 13.9167 mL 27.8334 mL
5 mM 0.5567 mL 2.7833 mL 5.5667 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (6.96 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación

Purity: 99.42%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7833 mL 13.9167 mL 27.8334 mL 69.5836 mL
5 mM 0.5567 mL 2.7833 mL 5.5667 mL 13.9167 mL
10 mM 0.2783 mL 1.3917 mL 2.7833 mL 6.9584 mL
15 mM 0.1856 mL 0.9278 mL 1.8556 mL 4.6389 mL
20 mM 0.1392 mL 0.6958 mL 1.3917 mL 3.4792 mL
25 mM 0.1113 mL 0.5567 mL 1.1133 mL 2.7833 mL
30 mM 0.0928 mL 0.4639 mL 0.9278 mL 2.3195 mL
40 mM 0.0696 mL 0.3479 mL 0.6958 mL 1.7396 mL
50 mM 0.0557 mL 0.2783 mL 0.5567 mL 1.3917 mL
60 mM 0.0464 mL 0.2319 mL 0.4639 mL 1.1597 mL
80 mM 0.0348 mL 0.1740 mL 0.3479 mL 0.8698 mL
100 mM 0.0278 mL 0.1392 mL 0.2783 mL 0.6958 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Florasulam
Cat. No.:
HY-B1845
Cantidad:
MCE Japan Authorized Agent: